Ehrlich R M, Shanberg A M, Asch M J, Kogan B, Kaplan L
J Urol. 1986 Jul;136(1 Pt 2):308-11. doi: 10.1016/s0022-5347(17)44851-8.
Bilateral nephrectomy was performed in 4 patients with bilateral Wilms tumor. The current philosophy regarding the need to preserve maximum renal parenchyma is discussed. New guidelines suggested by the National Wilms Tumor Study group discourage unilateral nephrectomy and partial nephrectomy at initial exploration for bilateral Wilms tumor. Alternatively, it is recommended that continued treatment with chemotherapy and/or radiation therapy followed by second and third-look operations to maximize preservation of renal parenchyma be done with bilateral nephrectomy as a last resort option.
对4例双侧肾母细胞瘤患者实施了双侧肾切除术。讨论了关于保留最大肾实质必要性的当前理念。国家肾母细胞瘤研究组提出的新指南不鼓励在初次探查双侧肾母细胞瘤时进行单侧肾切除和部分肾切除。另外，建议先进行化疗和/或放疗，然后进行二次和三次探查手术以最大程度保留肾实质，双侧肾切除术作为最后的选择。
