Chutko L S, Surushkina S Yu, Yakovenko E A, Anisimova T I, Volov M B, Rozhkova A V, Sergeev A V
Bekhtereva Institute of Human Brain, Russian Academy of Sciences, St. Petersburg, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(5. Vyp. 2):57-63. doi: 10.17116/jnevro20181185257.
To study comorbid cognitive impairments in children with enuresis and assess the efficacy and safety of cerebrolysin in treatment of comorbid pathology.
Seventy patients, aged from 7 to 10 years, with the primary monosymtomatic form of enuresis were examined. Enuresis was assessed by the mean number of 'wet' nights per week. Neuropsychological tests were administered to measure short-term auditory-verbal and visual memory as well as SNAP-1V inattention and TOVA impulsivity. Electroencephalography was used as well.
Children with enuresis performed lower on auditory-verbal and visual memory and attention tests compared to the patients of the control group. Electroencephalography showed activation deficit and synchronized effects of thalamic structures. The high efficacy of cerebrolysin (the improvement was seen in 80% of the patients) was demonstrated.
研究遗尿症患儿的共病认知障碍，并评估脑蛋白水解物治疗共病病理的疗效和安全性。
对70例年龄在7至10岁、患有原发性单症状型遗尿症的患者进行检查。通过每周“尿床”夜晚的平均次数评估遗尿症。进行神经心理学测试以测量短期听觉言语和视觉记忆以及SNAP-1V注意力不集中和TOVA冲动性。同时也使用了脑电图。
与对照组患者相比，遗尿症患儿在听觉言语和视觉记忆以及注意力测试中的表现较差。脑电图显示丘脑结构的激活缺陷和同步效应。证明了脑蛋白水解物的高效性（80%的患者有改善）。
