Aleshaki Joseph S, Cardwell Leah A, Muse Mikél E, Feldman Steven R
a Center for Dermatology Research, Department of Dermatology , Wake Forest School of Medicine , Winston-Salem , NC , USA.
b Department of Pathology , Wake Forest School of Medicine , Winston-Salem , NC , USA.
Expert Rev Pharmacoecon Outcomes Res. 2018 Dec;18(6):609-617. doi: 10.1080/14737167.2018.1512408. Epub 2018 Sep 10.
The emergence of immune-modulating drugs such as biologics has altered the treatment landscape for psoriasis. However, their use presents high financial costs to patients and healthcare systems. Patient demographic and socioeconomic status may influence adherence to biologic medications and usage of healthcare resources.
We performed a systematic literature review to summarize the available evidence pertaining to biologic medication adherence and resource use. PubMed was searched using the terms 'psoriasis and adherence' and 'psoriasis biologics resource use.'
Psoriasis patients utilize many healthcare resources. Adherence rates are typically higher for biologics than for other psoriasis treatment categories. However, adherence rates are still suboptimal.
生物制剂等免疫调节药物的出现改变了银屑病的治疗格局。然而，其使用给患者和医疗系统带来了高昂的经济成本。患者的人口统计学特征和社会经济状况可能会影响生物制剂药物的依从性以及医疗资源的使用。
我们进行了一项系统的文献综述，以总结有关生物制剂药物依从性和资源使用的现有证据。使用“银屑病与依从性”以及“银屑病生物制剂资源使用”等术语在PubMed上进行了检索。
银屑病患者使用多种医疗资源。生物制剂的依从率通常高于其他银屑病治疗类别。然而，依从率仍未达到最佳水平。
