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沙特阿拉伯利雅得一所大学附属医院葡萄膜炎患者白内障的发病率、危险因素和手术结果。

Incidence, Risk Factors and Surgical Outcomes of Cataract among Patients with Uveitis in a University Referral Hospital in Riyadh, Saudi Arabia.

机构信息

Department of Ophthalmology, King Saud University , Riyadh , Saudi Arabia.

Ophthalmology Department, College of Medicine, Majmaah University , Al Majma'ah , Saudi Arabia.

出版信息

Ocul Immunol Inflamm. 2019;27(7):1105-1113. doi: 10.1080/09273948.2018.1504970. Epub 2018 Aug 24.

DOI:10.1080/09273948.2018.1504970
PMID:30142008
Abstract

: To investigate incidence, risk factors, and surgical outcomes of cataract among uveitis patients. : Retrospective review of 1000 patients (1582 eyes). : At initial presentation, cataract was diagnosed in 290 (18.3%) eyes and was most common in eyes with anterior uveitis. Fuchs' uveitis, herpetic uveitis, and presumed tuberculous uveitis were leading clinical entities associated with cataract at presentation. During follow-up, cataract developed in additional 200 (12.6%) eyes and was most common in eyes with anterior uveitis. Significant risk factors at presentation included age >18 years, female gender, presence of keratic precipitates, hypopyon, and posterior synechiae. Among the 490 eyes with cataract, 204 underwent cataract extraction during follow-up period. Best corrected vision of ≥20/40 was achieved in 122 (60.1%) eyes. : Incidence of cataract differed depending on anatomic and etiologic diagnoses of uveitis. There is a significant association between severity of inflammation at presentation and development of cataract.

摘要

: 研究葡萄膜炎患者白内障的发病率、危险因素和手术结果。 : 回顾性分析了 1000 名患者(1582 只眼)。 : 在初次就诊时,290 只眼(18.3%)被诊断为白内障,其中以前葡萄膜炎的眼最常见。在初诊时,与白内障相关的主要临床实体是 Fuchs 葡萄膜炎、疱疹性葡萄膜炎和疑似结核性葡萄膜炎。在随访期间,另外 200 只眼(12.6%)发展为白内障,其中以前葡萄膜炎的眼最常见。初诊时的显著危险因素包括年龄>18 岁、女性、存在角膜后沉着物、前房积脓和虹膜后粘连。在 490 只有白内障的眼中,有 204 只在随访期间接受了白内障摘除术。122 只眼(60.1%)的最佳矫正视力≥20/40。 : 白内障的发病率取决于葡萄膜炎的解剖和病因诊断。炎症的严重程度与白内障的发生有显著关联。

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