Okubo Kazuki, Sato Akinori, Nakamoto Keitaro, Hatanaka Yuki, Isono Makoto, Hatanaka Mina, Suyama Yohsuke, Shinmoto Hiroshi, Asano Tomohiko
Department of Urology, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Department of Urology, National Defense Medical College, Tokorozawa, Saitama 359-8513, Japan.
Urology. 2018 Nov;121:e3-e4. doi: 10.1016/j.urology.2018.08.008. Epub 2018 Aug 21.
Bosniak category III renal cystic masses are often treated with surgical resection because of high risk of malignancy. Crizotinib is an anaplastic lymphoma kinase (ALK) inhibitor used to treat ALK gene-rearranged non-small cell lung cancer and reported to be associated with complex renal cyst formation. We herein report a case of Bosniak category III renal cysts occurred in a crizotinib-treated ALK gene-rearranged non-small cell lung cancer patients. The cysts regressed spontaneously after cessation of crizotinib and we could thus avoid unnecessary surgical resection.
