Stewart T H, Hollinshead A C, Harris J E, Raman S, Bélanger R, Crépeau A, Crook A F, Hirte W E, Hooper D, Klaassen D J, Rapp E F, Sachs H J
Can J Surg. 1977 Jul;20(4):370-7.
A radomized clinical trial of chemotherapy, immunization and immunochemotherapy among 55 patients with stages I and II carcinoma of the lung is reported. The survival rate in the immunized groups was significantly better (P = 0.001) than that in the nonimmunized groups. The results are discussed in the light of the reactivity of the patients to the specific cancer antigen.
报道了一项针对55例I期和II期肺癌患者进行化疗、免疫治疗和免疫化疗的随机临床试验。免疫组的生存率显著高于未免疫组(P = 0.001)。根据患者对特定癌症抗原的反应性对结果进行了讨论。