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如何改变你的想法:经颅直流电刺激刺激 Fp3 改变人类的刺激表示和学习。

How we can change your mind: Anodal tDCS to Fp3 alters human stimulus representation and learning.

机构信息

School of Psychology, College of Life and Environmental Sciences, University of Exeter, UK.

School of Psychology, College of Life and Environmental Sciences, University of Exeter, UK.

出版信息

Neuropsychologia. 2018 Oct;119:241-246. doi: 10.1016/j.neuropsychologia.2018.08.019. Epub 2018 Aug 23.

DOI:10.1016/j.neuropsychologia.2018.08.019
PMID:30144462
Abstract

The aim of the current work is to advance our understanding of both the mechanisms controlling perceptual learning and the face inversion effect. In the three double blind experiments reported here (total N = 144) we have shown that anodal tDCS stimulation (10 min at 1.5 mA) delivered over the left DLPFC at Fp3 affects perceptual learning and drastically reduces the, usually robust, face inversion effect. In Experiment 1, we found a significantly reduced inversion effect in the anodal group compared to that in the sham group. Experiment 2 replicated the pattern of results found in Experiment 1. In both experiments recognition performance for upright faces in the anodal group was significantly impaired compared to that in the sham group. Finally, using an active control in Experiment 3 (same behavioural task but different tDCS targeted brain area) we showed that the same Fp3 anodal tDCS stimulation effect is not obtained when a different brain area is targeted.

摘要

本研究旨在深入理解控制知觉学习和面孔倒置效应的机制。在我们报告的三项双盲实验中(总人数=144),我们发现,左侧背外侧前额叶 Fp3 施以 1.5 mA、10 分钟的阳极经颅直流电刺激(tDCS)会影响知觉学习,并显著降低通常较为显著的面孔倒置效应。在实验 1 中,我们发现与假刺激组相比,阳极刺激组的面孔倒置效应显著降低。实验 2 重复了实验 1 的结果模式。在这两项实验中,与假刺激组相比,阳极刺激组的正立面孔识别表现显著受损。最后,在实验 3 中使用主动对照(相同的行为任务,但采用不同的 tDCS 靶向脑区),我们表明,当靶向不同脑区时,不会产生相同的 Fp3 阳极 tDCS 刺激效果。

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Transcranial direct current stimulation (tDCS) eliminates the other-race effect (ORE) indexed by the face inversion effect for own versus other-race faces.经颅直流电刺激(tDCS)消除了面孔倒置效应(FIE)指标所反映的异族效应(ORE),该效应涉及自身种族面孔和异族种族面孔。
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Using transcranial Direct Current Stimulation (tDCS) to investigate why faces are and are not special.
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Transcranial direct current stimulation: a roadmap for research, from mechanism of action to clinical implementation.经颅直流电刺激:从作用机制到临床应用的研究路线图。
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