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使用心电图和心音图的无创胎儿监测:一项初步研究。

Non-invasive fetal monitoring using electrocardiography and phonocardiography: A preliminary study.

作者信息

Gobillot S, Fontecave-Jallon J, Equy V, Rivet B, Gumery P Y, Hoffmann P

机构信息

Grenoble-Alpes University Hospital, Obstetrical Care Unit, 38000 Grenoble, France; Laboratoire TIMC-IMAG, PRETA, 38700 La Tronche, France.

Laboratoire TIMC-IMAG, PRETA, 38700 La Tronche, France; Grenoble-Alpes University, 38400 Saint-Martin-d'Hères, France.

出版信息

J Gynecol Obstet Hum Reprod. 2018 Nov;47(9):455-459. doi: 10.1016/j.jogoh.2018.08.009. Epub 2018 Aug 23.

Abstract

BACKGROUND

Continuous fetal monitoring is commonly used during pregnancy and labor to assess fetal wellbeing. The most often used technology is cardiotocography (CTG), but this technique has major drawbacks in clinical use.

OBJECTIVES

Our aim is to test a non-invasive multimodal technique of fetal monitoring using phonocardiography (PCG) and electrocardiography (ECG) and to evaluate its feasibility in clinical practice, by comparison with CTG.

METHODS

This prospective open label study took place in a French university hospital. PCG and ECG signals were recorded using abdominal and thoracic sensors from antepartum women during the second half of pregnancy, simultaneously with CTG recording. Signals were then processed to extract fetal PCG and ECG and estimate fetal heart rate (FHR).

RESULTS

A total of 9 sets of recordings were evaluated. Very accurate fetal ECG and fetal PCG signals were recorded, enabling us to obtain FHR for several subjects. The FHR calculated from ECG was highly correlated with the FHR from the CTG reference (from 74% to 84% of correlation).

CONCLUSION

This work with preliminary signal processing algorithms proves the feasibility of the approach and constitutes the beginnings of a unique database that is needed to improve and validate the signal processing algorithms.

摘要

背景

孕期和分娩期间通常采用连续胎儿监测来评估胎儿健康状况。最常用的技术是胎心宫缩图(CTG),但该技术在临床应用中有重大缺陷。

目的

我们的目标是测试一种使用心音图(PCG)和心电图(ECG)的非侵入性多模态胎儿监测技术,并通过与CTG比较来评估其在临床实践中的可行性。

方法

这项前瞻性开放标签研究在一家法国大学医院进行。在妊娠后半期,使用腹部和胸部传感器记录产前女性的心音图和心电图信号,同时记录CTG。然后对信号进行处理,以提取胎儿心音图和心电图,并估计胎儿心率(FHR)。

结果

共评估了9组记录。记录到了非常准确的胎儿心电图和胎儿心音图信号,使我们能够为多个受试者获取胎儿心率。从心电图计算出的胎儿心率与CTG参考值的胎儿心率高度相关(相关性为74%至84%)。

结论

这项采用初步信号处理算法的研究证明了该方法的可行性,并构成了一个独特数据库的开端,该数据库是改进和验证信号处理算法所必需的。

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