CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Environ Pollut. 2018 Nov;242(Pt B):1527-1534. doi: 10.1016/j.envpol.2018.08.046. Epub 2018 Aug 18.
The levels and spatial distribution of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in freshwater products from Northeast China were investigated by gas chromatography coupled to isotope dilution high-resolution mass spectrometry. All samples were on-spot sampled from main production regions of freshwater products in Northeast China, and these samples were used to systematically assess the potential health risks of OCPs and PCBs associated with consumption of these fishery products. Dichlorodiphenyltrichloroethanes (DDTs), hexachlorocyclohexane (HCHs), hexachlorobenzene (HCB) and PCBs were the major pollutants with 100% detection rates, and their levels ranged from 0.086 to 58, 0.038-3.3, 0.093-4.5 and 0.032-1.4 ng g wet weight, respectively. The estimated dietary intakes of these contaminants were all below their corresponding acceptable daily intakes. Significant regional differences in the levels of OCPs and PCBs (P ≦ 0.001) were found in samples from Liaoning and Inner Mongolia. The results showed that the concentrations of targeted contaminants in aquatic products had species-specific characteristics, and the levels of targeted pollutants in Oncorhynchus mykiss and Eriocheir sienesis were significantly higher than those in other aquatic product species. Advisories on ten species of aquatic products suggested that consumption of Eriocheir sinensis, Oncorhynchus mykiss and Cyprinus carpio at a rate exceeding 15 meals per month would pose a cancer risk. A health risk assessment indicated that exposure to these pollutants through freshwater products consumption would cause a non-ignorable potential carcinogenic risk to humans.
采用气相色谱-同位素稀释高分辨质谱法研究了中国东北地区淡水产品中有机氯农药（OCPs）和多氯联苯（PCBs）的水平和空间分布。所有样品均现场采集于中国东北地区淡水产品主要产区，用于系统评估与食用这些水产品相关的 OCPs 和 PCBs 的潜在健康风险。滴滴涕（DDTs）、六氯环己烷（HCHs）、六氯苯（HCB）和 PCBs 是主要污染物，检出率为 100%，其浓度范围分别为 0.086-58、0.038-3.3、0.093-4.5 和 0.032-1.4ng/g 湿重。这些污染物的估计膳食摄入量均低于各自的可接受日摄入量。来自辽宁和内蒙古的样品中 OCPs 和 PCBs 的水平存在显著的区域差异（P≤0.001）。结果表明，目标污染物在水产动物中的浓度具有物种特异性，虹鳟和中华绒螯蟹中的目标污染物浓度明显高于其他水产动物。对 10 种水产动物的建议表明，每月食用超过 15 餐的中华绒螯蟹、虹鳟和鲤鱼可能会带来癌症风险。健康风险评估表明，通过食用淡水产品摄入这些污染物会对人类造成不可忽视的潜在致癌风险。
