DeMauro Sara B
Division of Neonatology, The Children's Hospital of Philadelphia, 2nd Floor Main Building, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
Clin Perinatol. 2018 Sep;45(3):439-452. doi: 10.1016/j.clp.2018.05.006.
The rate of bronchopulmonary dysplasia (BPD) in preterm infants is increasing; this trend reflects, in part, improved survival among extremely premature infants. BPD is associated with adverse developmental and medical outcomes in early childhood and at least through school age. Therefore, BPD imposes a significant burden on infants and children, their families, and society. Many interventions to decrease BPD and the sequelae of BPD have been studied; few to date have been proved to decrease both BPD and later disability.
早产儿支气管肺发育不良(BPD)的发生率正在上升;这一趋势部分反映了极早产儿存活率的提高。BPD与儿童早期直至至少学龄期的不良发育和医学后果相关。因此,BPD给婴幼儿及其家庭和社会带来了沉重负担。人们已经研究了许多降低BPD及其后遗症的干预措施;迄今为止,几乎没有被证明能同时降低BPD和后期残疾率的措施。