非阵发性房颤患者转子消融的影响：OASIS 试验长期随访中按方案人群的研究结果。
Impact of rotor ablation in non-paroxysmal AF patients: Findings from the per-protocol population of the OASIS trial at long-term follow-up.
机构信息
Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA.
Texas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA; Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
出版信息
Am Heart J. 2018 Nov;205:145-148. doi: 10.1016/j.ahj.2018.05.021. Epub 2018 Jul 31.
The objective of this study was to evaluate the long-term efficacy of FIRM ablation with PVAI vs PVAI plus posterior wall isolation (PWI) and non-PV trigger ablation in persistent (PeAF) and long-standing persistent AF (LSPAF) patients. The procedure time was recorded to be 180.6 ± 35.9 and 124.03 ± 45.4 minutes in the FIRM+PVI and PVI + PWI + non-PV trigger ablation group respectively. At 24-month follow-up, 24% (95% CI 8.7%-37.8%) in the FIRM-ablation group and 48% (95% CI 27.6-63.3%) in the non-PV trigger ablation group remained arrhythmia-free off-antiarrhythmic drugs after a single procedure. Clinical Trial Registration:ClinicalTrials.gov (Identifier: NCT02533843).
本研究旨在评估 FIRM 消融联合 PVAI 与 PVAI 联合后间隔隔离（PWI）和非 PV 触发灶消融在持续性（PeAF）和长程持续性房颤（LSPAF）患者中的长期疗效。记录的手术时间分别为 FIRM+PVI 组 180.6±35.9 分钟和 PVI+PWI+非 PV 触发灶消融组 124.03±45.4 分钟。在 24 个月的随访中，FIRM 消融组中 24%（95%CI 8.7%-37.8%）和非 PV 触发灶消融组中 48%（95%CI 27.6-63.3%）的患者在单次手术后，抗心律失常药物治疗下仍保持无心律失常。临床试验注册：ClinicalTrials.gov（标识符：NCT02533843）。
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