• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

血管腔内主动脉手术中预防脊髓缺血的分期手术

Staged procedures for prevention of spinal cord ischemia in endovascular aortic surgery.

作者信息

Heidemann F, Tsilimparis N, Rohlffs F, Debus E S, Larena-Avellaneda A, Wipper S, Kölbel T

机构信息

German Aortic Center Hamburg, Department and Outpatient Clinic for Vascular Medicine, University Heart Center, University Hospital Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.

出版信息

Gefasschirurgie. 2018;23(Suppl 2):39-45. doi: 10.1007/s00772-018-0410-z. Epub 2018 Jul 2.

DOI:10.1007/s00772-018-0410-z
PMID:30147243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6096720/
Abstract

BACKGROUND

Spinal cord ischemia with development of paraplegia is the most relevant complication of thoracoabdominal aortic surgery caused by compromising the segmental arteries. To prevent this devastating complication in endovascular aortic surgery, staging procedures have been developed to reinforce collateral blood flood to the spinal cord.

RESULTS

In patients with a medium to high risk for spinal cord ischemia, staged aortic repair is recommended. The classical staged repair is the two-step repair with delayed implantation of the aortic stent grafts. Additionally, more recent methods for short-term salvage of segmental artery perfusion by leaving an endoleak have been developed. Perfusion branches, delayed bridging stents as well as the open branch technique are among these methods. The latest option of staged repair is minimally invasive segmental artery embolization.

CONCLUSION

Besides the nonsurgical options for monitoring and therapy of spinal cord ischemia, various staging procedures are available, which can be implemented depending on the patient and the aortic anatomy. Evidence that underlines staged repair for endovascular treatment of thoracoabdominal aortic pathologies is mostly based on retrospective studies.

摘要

背景

脊髓缺血并发展为截瘫是胸腹主动脉手术最相关的并发症,由节段动脉受压引起。为防止血管腔内主动脉手术中出现这种毁灭性并发症,已开发出分期手术以加强脊髓的侧支血流灌注。

结果

对于脊髓缺血中高风险患者,建议进行分期主动脉修复。经典的分期修复是两步修复,延迟植入主动脉支架移植物。此外,还开发了通过保留内漏进行节段动脉灌注短期挽救的最新方法。灌注分支、延迟桥接支架以及开放分支技术都属于这些方法。分期修复的最新选择是微创节段动脉栓塞。

结论

除了脊髓缺血监测和治疗的非手术选择外,还有各种分期手术可供选择,可根据患者和主动脉解剖结构实施。强调胸腹主动脉病变血管腔内治疗分期修复的证据大多基于回顾性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/b630019d6c6c/772_2018_410_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/00ddca39a3ed/772_2018_410_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/7613619f9dbd/772_2018_410_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/8ebddd0cff94/772_2018_410_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/74d7edd59719/772_2018_410_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/b630019d6c6c/772_2018_410_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/00ddca39a3ed/772_2018_410_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/7613619f9dbd/772_2018_410_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/8ebddd0cff94/772_2018_410_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/74d7edd59719/772_2018_410_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9513/6096720/b630019d6c6c/772_2018_410_Fig5_HTML.jpg

相似文献

1
Staged procedures for prevention of spinal cord ischemia in endovascular aortic surgery.血管腔内主动脉手术中预防脊髓缺血的分期手术
Gefasschirurgie. 2018;23(Suppl 2):39-45. doi: 10.1007/s00772-018-0410-z. Epub 2018 Jul 2.
2
First-in-man endovascular preconditioning of the paraspinal collateral network by segmental artery coil embolization to prevent ischemic spinal cord injury.首例经皮节段动脉线圈栓塞治疗脊柱旁侧支网络的血管内预处理,以预防缺血性脊髓损伤。
J Thorac Cardiovasc Surg. 2015 Apr;149(4):1074-9. doi: 10.1016/j.jtcvs.2014.12.025. Epub 2014 Dec 18.
3
Neuromonitoring, Cerebrospinal Fluid Drainage, and Selective Use of Iliofemoral Conduits to Minimize Risk of Spinal Cord Injury During Complex Endovascular Aortic Repair.神经监测、脑脊液引流以及选择性使用髂股血管移植物以降低复杂血管腔内主动脉修复术中脊髓损伤风险
J Endovasc Ther. 2016 Feb;23(1):139-49. doi: 10.1177/1526602815620898. Epub 2015 Dec 4.
4
Minimally invasive segmental artery coil embolization for preconditioning of the spinal cord collateral network before one-stage descending and thoracoabdominal aneurysm repair.微创节段动脉弹簧圈栓塞术用于一期降主动脉和胸腹主动脉瘤修复术前脊髓侧支循环网络的预处理。
Innovations (Phila). 2014 Jan-Feb;9(1):60-5. doi: 10.1097/IMI.0000000000000038.
5
Spinal cord ischemia in open and endovascular thoracoabdominal aortic aneurysm repair: new concepts.开放及血管腔内胸腹主动脉瘤修复术中的脊髓缺血:新概念
J Cardiovasc Surg (Torino). 2014 Apr;55(2 Suppl 1):159-68.
6
Development of Collaterals to the Spinal Cord after Endovascular Stent Graft Repair of Thoracic Aneurysms.胸主动脉瘤血管内支架植入修复术后脊髓侧支循环的发展
Eur J Vasc Endovasc Surg. 2016 Dec;52(6):801-807. doi: 10.1016/j.ejvs.2016.09.010. Epub 2016 Oct 21.
7
Endovascular occlusion of segmental arteries feeding the anterior spinal artery to stage endovascular thoracoabdominal aortic repair.为分期进行血管内胸腹主动脉修复术,对供应脊髓前动脉的节段动脉进行血管内闭塞。
JTCVS Open. 2024 Feb 29;18:1-8. doi: 10.1016/j.xjon.2024.02.016. eCollection 2024 Apr.
8
[Prevention of Spinal Cord Ischemia During Thoracic Endovascular Aortic Repair].[胸主动脉腔内修复术中脊髓缺血的预防]
Kyobu Geka. 2017 Apr;70(4):251-256.
9
Evaluation of visible spinal arteries on computed tomography angiography before and after branched stent graft repair for thoracoabdominal aortic aneurysm.胸腹主动脉瘤分支型覆膜支架修复术前及术后计算机断层扫描血管造影对可见脊髓动脉的评估
J Vasc Surg. 2017 Jun;65(6):1577-1583. doi: 10.1016/j.jvs.2016.10.118.
10
Motor evoked potential-guided segmental artery revascularization during open thoracoabdominal aortic aneurysm surgery after coil embolization as a part of the minimally invasive staged segmental artery coil embolization concept.作为微创分期节段动脉线圈栓塞概念的一部分,在开放胸腹主动脉瘤手术中,于线圈栓塞后进行运动诱发电位引导下的节段动脉血运重建。
J Vasc Surg Cases Innov Tech. 2022 Mar 8;8(2):206-209. doi: 10.1016/j.jvscit.2022.02.004. eCollection 2022 Jun.

引用本文的文献

1
Staged Endovascular and Open Surgical Repair of Multiple High-Risk Thoracoabdominal Aortic Aneurysms Following Initial Presentation With a Ruptured Juxtarenal Aneurysm: A Case Report.初次表现为肾旁动脉瘤破裂后多高危胸腹主动脉瘤的分期血管内修复与开放手术修复:病例报告
Cureus. 2025 Jul 2;17(7):e87195. doi: 10.7759/cureus.87195. eCollection 2025 Jul.
2
Fiber Optic RealShape (FORS) and three-dimensional overlay technology in preemptive segmental artery embolization to reduce the risk of spinal cord ischemia prior to fenestrated endovascular aortic aneurysm repair.在开窗式血管内主动脉瘤修复术前,使用光纤实时形态(FORS)和三维叠加技术进行节段性动脉预栓塞以降低脊髓缺血风险。
J Vasc Surg Cases Innov Tech. 2025 Apr 7;11(4):101803. doi: 10.1016/j.jvscit.2025.101803. eCollection 2025 Aug.
3

本文引用的文献

1
Temporary Perfusion Branches to Decrease Spinal Cord Ischemia in the Endovascular Treatment of Thoraco-Abdominal Aortic Aneurysms: Based on a Presentation at the 2013 VEITH Symposium, November 19-23, 2013 (New York, NY, USA).用于降低胸腹主动脉瘤血管内治疗中脊髓缺血的临时灌注分支:基于2013年11月19日至23日在美国纽约举行的第2013届VEITH研讨会的报告
Aorta (Stamford). 2015 Apr 1;3(2):56-60. doi: 10.12945/j.aorta.2015.14-045. eCollection 2015 Apr.
2
The "Open Branch" Technique: A New Way to Prevent Paraplegia After Total Endovascular Repair of Thoracoabdominal Aneurysm.“开放分支”技术:胸腹主动脉瘤全腔内修复术后预防截瘫的新方法。
Catheter Cardiovasc Interv. 2016 Mar;87(4):773-80. doi: 10.1002/ccd.26373. Epub 2015 Dec 28.
3
Prevention and Management of Spinal Cord Ischemia After Aortic Surgery: An Umbrella Review.主动脉手术后脊髓缺血的预防与管理:一项伞状综述
Brain Sci. 2025 Apr 17;15(4):409. doi: 10.3390/brainsci15040409.
4
Three-Staged Surgical Hybrid Treatment for an Extended Thoracoabdominal Aneurysm in a High-Risk Patient: A Case Report.高危患者胸腹主动脉瘤的三阶段外科杂交治疗:病例报告
Cureus. 2024 Dec 30;16(12):e76616. doi: 10.7759/cureus.76616. eCollection 2024 Dec.
5
A dedicated preventive protocol sustainably avoids spinal cord ischemia after endovascular aortic repair.一种专门的预防方案可持续避免血管腔内主动脉修复术后脊髓缺血。
Front Cardiovasc Med. 2024 Aug 1;11:1440674. doi: 10.3389/fcvm.2024.1440674. eCollection 2024.
6
Intra- and Early Post-Operative Factors Affecting Spinal Cord Ischemia in Patients Undergoing Fenestrated and Branched Endovascular Aortic Repair.影响接受开窗及分支型血管内主动脉修复术患者脊髓缺血的术中及术后早期因素
J Clin Med. 2024 Jul 8;13(13):3978. doi: 10.3390/jcm13133978.
7
[Ischemia-related compartment syndromes in vascular surgery].[血管外科中与缺血相关的骨筋膜室综合征]
Chirurgie (Heidelb). 2024 Jul;95(7):513-519. doi: 10.1007/s00104-024-02080-3. Epub 2024 Apr 18.
8
A direct aorta to segmental artery bypass for prevention of spinal cord ischemia after endovascular aortic repair.一种用于预防血管腔内主动脉修复术后脊髓缺血的直接主动脉至节段动脉旁路术。
J Vasc Surg Cases Innov Tech. 2024 Feb 6;10(3):101446. doi: 10.1016/j.jvscit.2024.101446. eCollection 2024 Jun.
9
Open, closed or a bit of both: a systematic review and meta-analysis of staged thoraco-abdominal aortic aneurysm repair.开放手术、腔内修复术或两者结合:胸腹主动脉瘤分期修复的系统评价与荟萃分析
Ann Cardiothorac Surg. 2023 Sep 28;12(5):418-428. doi: 10.21037/acs-2023-scp-20. Epub 2023 Sep 19.
10
Neuronal Pre- and Postconditioning via Toll-like Receptor 3 Agonist or Extracorporeal Shock Wave Therapy as New Treatment Strategies for Spinal Cord Ischemia: An In Vitro Study.通过Toll样受体3激动剂或体外冲击波疗法进行神经元预处理和后处理作为脊髓缺血的新治疗策略:一项体外研究
J Clin Med. 2022 Apr 11;11(8):2115. doi: 10.3390/jcm11082115.
First-in-man endovascular preconditioning of the paraspinal collateral network by segmental artery coil embolization to prevent ischemic spinal cord injury.首例经皮节段动脉线圈栓塞治疗脊柱旁侧支网络的血管内预处理,以预防缺血性脊髓损伤。
J Thorac Cardiovasc Surg. 2015 Apr;149(4):1074-9. doi: 10.1016/j.jtcvs.2014.12.025. Epub 2014 Dec 18.
4
Staged endovascular repair of thoracoabdominal aortic aneurysms limits incidence and severity of spinal cord ischemia.胸腹主动脉瘤的分期血管内修复术可降低脊髓缺血的发生率和严重程度。
J Vasc Surg. 2015 Feb;61(2):347-354.e1. doi: 10.1016/j.jvs.2014.09.011. Epub 2014 Oct 23.
5
Editor's choice--Temporary aneurysm sac perfusion as an adjunct for prevention of spinal cord ischemia after branched endovascular repair of thoracoabdominal aneurysms.编辑精选--分支型腔内修复胸主动脉腹主动脉瘤后,临时动脉瘤囊内灌注作为预防脊髓缺血的辅助手段。
Eur J Vasc Endovasc Surg. 2014 Sep;48(3):258-65. doi: 10.1016/j.ejvs.2014.05.020. Epub 2014 Jul 2.
6
Minimally invasive segmental artery coil embolization for preconditioning of the spinal cord collateral network before one-stage descending and thoracoabdominal aneurysm repair.微创节段动脉弹簧圈栓塞术用于一期降主动脉和胸腹主动脉瘤修复术前脊髓侧支循环网络的预处理。
Innovations (Phila). 2014 Jan-Feb;9(1):60-5. doi: 10.1097/IMI.0000000000000038.
7
Endovascular coil embolization of segmental arteries prevents paraplegia after subsequent thoracoabdominal aneurysm repair: an experimental model.节段性动脉血管内线圈栓塞可预防胸腹主动脉瘤修复后继发性截瘫:实验模型。
J Thorac Cardiovasc Surg. 2014 Jan;147(1):220-6. doi: 10.1016/j.jtcvs.2013.09.022. Epub 2013 Nov 9.
8
Hypogastric and subclavian artery patency affects onset and recovery of spinal cord ischemia associated with aortic endografting.腹主动脉和锁骨下动脉通畅情况影响主动脉瘤腔内修复术后脊髓缺血的发生和恢复。
J Vasc Surg. 2014 Jan;59(1):89-94. doi: 10.1016/j.jvs.2013.07.007. Epub 2013 Nov 1.
9
Mechanisms of symptomatic spinal cord ischemia after TEVAR: insights from the European Registry of Endovascular Aortic Repair Complications (EuREC).TEVAR 后症状性脊髓缺血的机制:来自血管内主动脉修复并发症欧洲登记处(EuREC)的见解。
J Endovasc Ther. 2012 Feb;19(1):37-43. doi: 10.1583/11-3578.1.
10
Elective sac perfusion to reduce the risk of neurologic events following endovascular repair of thoracoabdominal aneurysms.择期行腹主动脉瘤腔内修复术后的选择性内脏动脉灌注以降低神经系统事件的风险。
J Vasc Surg. 2012 Apr;55(4):1202-5. doi: 10.1016/j.jvs.2011.10.079. Epub 2012 Feb 2.