Frol'kis V V, Kol'tover V K, Gorban' E N, Paramonova G I, Shcherbitskaia E V
Vopr Med Khim. 1986 May-Jun;32(3):79-81.
Liver EPR signals were studied in adult (8 months) and old (24 months) Wistar male rats after the 30 days course of enterosorption carried out daily. The signals were analyzed at the values of g = 1.94, 2.00, 2.25, 2.035, 2.16, 2.10 and 1.97. Age-dependent differences were found in liver EPR signals of intact animals, i. e. the intensity of signals of g = 1.97, 2.00, 1.97 and 2.25 was decreased in old animals. In adult animals enterosorption caused a decrease of signals of g = 2.25, 1.94, 2.00, 2.16 and 2.10. In old animals the treatment led to a dissimilar effect: the intensity of signals was decreased at the ranges of g = 2.25, distinctly increased at g = 1.97 and unaltered at the other EPR signal values studied. Geroprotective action of enterosorption is discussed considering the decrease in enzymatic activity of electron transport systems due to the treatment studied.
对成年（8个月）和老年（24个月）雄性Wistar大鼠进行为期30天的每日肠吸附治疗后，研究其肝脏电子顺磁共振（EPR）信号。在g = 1.94、2.00、2.25、2.035、2.16、2.10和1.97值下分析信号。在未处理动物的肝脏EPR信号中发现了年龄依赖性差异，即老年动物中g = 1.97、2.00、1.97和2.25信号的强度降低。在成年动物中，肠吸附导致g = 2.25、1.94、2.00、2.16和2.10信号降低。在老年动物中，该治疗导致不同的效果：g = 2.25范围内信号强度降低，g = 1.97时明显增加，而在所研究的其他EPR信号值处未改变。考虑到所研究治疗导致电子传输系统酶活性降低，讨论了肠吸附的老年保护作用。
