胰腺导管腺癌扩大多脏器切除术后的肾移植
Kidney Transplantation after Extended Multivisceral Resection for Pancreatic Ductal Adenocarcinoma.
作者信息
Lapshyn Hryhoriy, Bolm Louisa, Nitschke Martin, Luebke Andreas M, Izbicki Jakob R, Vashist Yogesh K, Keck Tobias, Wellner Ulrich F
机构信息
Clinic for Surgery, University Clinic Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
Department of Internal Medicine I, University Hospital of Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
出版信息
Case Rep Transplant. 2018 Jul 26;2018:3757382. doi: 10.1155/2018/3757382. eCollection 2018.
Long-term survival in patients with pancreatic ductal adenocarcinoma (PDAC) is limited. Consequently, solid organ transplantation in PDAC patients is usually not considered. This is the first case report of kidney transplantation (KT) in a 57-year-old female patient after extended multivisceral resection for PDAC of the distal pancreas who had developed end-stage renal disease (ESRD) due to toxic kidney damage by chemotherapy. 13,5 years after initial PDAC-operation and 3 years after KT the patient remains in a good general health condition with sufficient function of the kidney allograft without local tumor recurrence or distant metastasis.
胰腺导管腺癌（PDAC）患者的长期生存率有限。因此，通常不考虑对PDAC患者进行实体器官移植。这是首例关于一名57岁女性患者肾移植（KT）的病例报告，该患者因远端胰腺PDAC接受扩大多脏器切除术后，因化疗导致的中毒性肾损伤发展为终末期肾病（ESRD）。在初次PDAC手术13.5年后和KT手术3年后，患者总体健康状况良好，同种异体肾移植功能良好，无局部肿瘤复发或远处转移。
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