Mansha Muhammad Atif, Khan Agha Muhammad Hammad, Abbasi Ahmed Nadeem N, Tariq Muhammad Usman U, Mushtaq Naureen, Tariq Maria, Waheed Asmara
Oncology, Aga Khan University, Karachi, PAK.
Pathology & Laboratory Medicine, Aga Khan University, Karachi, PAK.
Cureus. 2018 Jun 22;10(6):e2863. doi: 10.7759/cureus.2863.
Primary spinal cord glioblastoma multiforme involving the conus medullaris is an uncommon entity with poor outcomes. An aggressive multimodality treatment approach has been used, but prognosis remains same. There are no guidelines for the treatment of patients with spinal glioblastoma multiforme (GBM). We highlight the case of a child diagnosed with conal GBM. He was treated with definitive surgery followed by adjuvant concurrent chemoradiation. After completion of treatment, he showed a temporary symptomatic improvement, but later on his condition deteriorated. We elaborate the stepwise treatment approach employed in this patient.
原发性脊髓多形性胶质母细胞瘤累及圆锥是一种罕见的疾病,预后较差。已采用积极的多模式治疗方法,但预后仍然相同。目前尚无脊髓多形性胶质母细胞瘤(GBM)患者的治疗指南。我们重点介绍一名被诊断为圆锥GBM的儿童病例。他接受了根治性手术,随后进行辅助同步放化疗。治疗完成后,他出现了短暂的症状改善,但后来病情恶化。我们详细阐述了该患者采用的逐步治疗方法。