Mihai Mihaela, Manole Alina, Dascălu Cristina Gena, Moraru D, Duca Elena, Manole M, Boldureanu D
Rev Med Chir Soc Med Nat Iasi. 2016 Jul-Sep;120(3):680-7.
The acute gastroenteritis is a population health problem, frequently met everywhere in the world. In Romania, for certain etiologies the reporting is compulsory. Also, these infections are reported in the TESSy system, too (The European Surveillance System). In this context, antibiotics therapy and antibiotics resistance have a particular importance. The study aim was to assess the prevalence of bacterial pathogens involved in the etiology of acute gastroenteritis (AGE) on the Iaşi County, Romania and the surrounding areas and the determination of the profile of resistance to the antibiotics for the identified agents. Material and methods: 72 strains of isolated and identified bacterial agents involved in the acute gastroenteritis (AGE) in the case of children (0-14 years), with the exception of the Campylobacter spp., in the municipality of Iasi and its surrounding areas were studied in 2012, during the surveillance period of AGE (May to October). Results: The most frequent has been the Salmonella spp. (63.9%) from which the S. enterica Thyphimurium in 21 cases (29.2%) and S. enteritidis in 7 cases (9.7%), followed by E. coli (20.8%) from which E. coli O:127 in 3 cases (4.2%), Shigella sonnei S (13.9%) and Yersinia enterocolitica (1.4%). In the case of the children from the group of 0-1 year, the Salmonella enterica Thyphimurium has been the pathogenic agent most frequently encountered (6 cases – 29.2%), followed by Salmonella Colindale, S. enteritidis, Shigella sonnei S, E. coli O:127 registered with a frequency of 5.6%. The antibiotic resistance rates are high in the case of ampicillin (43.1%), tetracycline (31.9%), amoxicillin – clavulanic acid (26.4%), trimethoprim/ sulfametoxazole (22.2%), sulfonamides (11.1%). Conclusions: The antibiotic resistance rates are high in the case of ampicillin, tetracycline, amoxicillin – clavulanic acid, trimethoprim/ sulfametoxazole, sulfonamides.
急性肠胃炎是一个全球性的公共卫生问题，在世界各地都很常见。在罗马尼亚，某些病因的病例报告是强制性的。此外，这些感染也在TESSy系统（欧洲监测系统）中进行报告。在这种背景下，抗生素治疗和抗生素耐药性具有特殊的重要性。本研究旨在评估罗马尼亚雅西县及周边地区急性肠胃炎（AGE）病因中涉及的细菌病原体的流行情况，以及确定所鉴定病原体的抗生素耐药性特征。材料与方法：2012年在雅西市及其周边地区，对72株从0至14岁儿童急性肠胃炎（AGE）病例中分离并鉴定出的细菌病原体（弯曲杆菌属除外）进行了研究，研究时段为AGE监测期（5月至10月）。结果：最常见的是沙门氏菌属（63.9%），其中肠炎沙门氏菌鼠伤寒亚种21例（29.2%），肠炎沙门氏菌肠炎亚种7例（9.7%），其次是大肠杆菌（20.8%），其中大肠杆菌O:127 3例（4.2%），宋内志贺氏菌S（13.9%）和小肠结肠炎耶尔森氏菌（1.4%）。在0至1岁组儿童中，肠炎沙门氏菌鼠伤寒亚种是最常遇到的病原体（6例 - 29.2%），其次是科林代尔沙门氏菌、肠炎沙门氏菌肠炎亚种、宋内志贺氏菌S、大肠杆菌O:127，发生率为5.6%。氨苄西林（43.1%）、四环素（31.9%）、阿莫西林 - 克拉维酸（26.4%）、甲氧苄啶/磺胺甲恶唑（22.2%）、磺胺类药物（11.1%）的抗生素耐药率较高。结论：氨苄西林、四环素、阿莫西林 - 克拉维酸、甲氧苄啶/磺胺甲恶唑、磺胺类药物的抗生素耐药率较高。
