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慢性闭塞性颈内动脉的评估与再通:颈动脉内膜切除术与血管腔内血管成形术联合手术

Estimation and Recanalization of Chronic Occluded Internal Carotid Artery: Hybrid Operation by Carotid Endarterectomy and Endovascular Angioplasty.

作者信息

Liu Bing, Wei Wei, Wang Yongli, Yang Xinyu, Yue Shuyuan, Zhang Jianning

机构信息

Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin Neurological Institute, Tianjin, China.

Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin Neurological Institute, Tianjin, China.

出版信息

World Neurosurg. 2018 Dec;120:e457-e465. doi: 10.1016/j.wneu.2018.08.104. Epub 2018 Aug 25.

Abstract

OBJECTIVE

Proper treatment for chronic occluded internal carotid artery (ICA) has not been determined. Endovascular recanalization may cause arterial injury and distal embolism. Hybrid recanalization for chronic occluded ICA was performed, and its safety and effectiveness were estimated.

METHODS

From March 2011 to March 2017, 21 patients were treated by hybrid recanalization with >1 year of follow-up. The ICA was totally occluded from the cervical segment to the cavernous, ophthalmic, or supraclinoid segment. Clinical characteristics, treatment strategy, recanalization rate, and main adverse events were reviewed retrospectively.

RESULTS

Initial recanalization was achieved in 15 patients (71.4%). Successful revascularization was more likely if the ICA was occluded with the plaque at the carotid bifurcation and the thrombus anterograde to the cavernous segment. There was no carotid dissection or intracranial hemorrhage. There were no new postprocedural neurologic deficits. Among 14 patients who underwent successful recanalization with follow-up, 1 patient had a repeat occlusion and another experienced about 50% restenosis.

CONCLUSIONS

Hybrid recanalization by carotid endarterectomy and arterial angioplasty is a safe treatment method for chronic totally occluded ICA. Recanalization was more likely to be successful if the ICA was occluded by the plaque at the carotid bifurcation with the thrombus anterograde to the cavernous segment than if the artery was occluded by the plaque at the ophthalmic or supraclinoid segment with the thrombus retrograde to the cervical segment.

摘要

目的

慢性颈内动脉(ICA)闭塞的恰当治疗方法尚未确定。血管内再通可能导致动脉损伤和远端栓塞。对慢性颈内动脉闭塞进行了杂交再通治疗,并评估了其安全性和有效性。

方法

2011年3月至2017年3月,21例患者接受了杂交再通治疗,随访时间超过1年。颈内动脉从颈段至海绵窦段、眼段或床突上段完全闭塞。回顾性分析临床特征、治疗策略、再通率和主要不良事件。

结果

15例患者(71.4%)实现了初始再通。如果颈内动脉在颈动脉分叉处被斑块阻塞且血栓向海绵窦段顺行,则更有可能成功实现血管重建。未发生颈动脉夹层或颅内出血。术后无新的神经功能缺损。在14例接受成功再通并随访的患者中,1例出现再次闭塞,另1例出现约50%的再狭窄。

结论

颈动脉内膜切除术和动脉血管成形术进行的杂交再通是慢性颈内动脉完全闭塞的一种安全治疗方法。与颈内动脉在眼段或床突上段被斑块阻塞且血栓向颈段逆行相比,如果颈内动脉在颈动脉分叉处被斑块阻塞且血栓向海绵窦段顺行,则再通更有可能成功。

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