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胫骨平台平整截骨术与胫骨结节前移术——一项系统评价

Tibial plateau leveling osteotomy and tibial tuberosity advancement - a systematic review.

作者信息

Beer Patricia, Bockstahler Barbara, Schnabl-Feichter Eva

出版信息

Tierarztl Prax Ausg K Kleintiere Heimtiere. 2018 Aug;46(4):223-235. doi: 10.15654/TPK-170486. Epub 2018 Aug 27.

Abstract

OBJECTIVE

The optimal surgical technique for treatment of cranial cruciate ligament rupture in canine has been scientifically discussed for decades. Despite the continuous debate, proximal tibial osteotomies such as tibial plateau leveling osteotomy (TPLO) and tibial tuberosity advancement (TTA) are increasingly common. The objective of this review was to systematically evaluate the literature reporting outcome and complications associated with TPLO and TTA.

MATERIALS AND METHODS

A systematic search of literature databases identified articles published from August 2004 to February 2016 describing evaluations of short- or longterm outcomes as well as complications following TPLO or TTA.

RESULTS

Ninety-one studies were included in this review and assigned to one out of four evidence levels. Of those, 89 studies provided the lowest evidence level and only two were assigned to the third-best evidence level. A comparison of subjective gait analyses could not detect differences in the decrease of lameness between TPLO and TTA, while objective gait analysis supports the superiority of TPLO. Fewer patients treated with TPLO were diagnosed with postoperative joint instability and TPLO had a lower percent increase of osteoarthritis (OA) after surgery. Owner satisfaction was high for both techniques. For TPLO and TTA the average total, minor, major and catastrophic complication rates were 15.9 % and 20.8 %, 7.9 % and 11.6 %, 5.2 % and 13.2 % as well as 0.8 % and 5.6 %, respectively.

CONCLUSION AND CLINICAL SIGNIFICANCE

The assessed literature supports the hypothesis that TPLO is associated with lower complication rates, an improved clinical-functional outcome and less increase of OA compared to TTA. The results are indicative for a long-term restoration of normal limb function after TPLO. However, the strength of available evidence and the comparability of each study's results were poor and more comparative studies are needed to draw strong conclusions towards the superiority of the TPLO over the TTA.

摘要

目的

数十年来一直在科学地探讨治疗犬颅交叉韧带断裂的最佳手术技术。尽管争论不断,但诸如胫骨平台水平截骨术(TPLO)和胫骨结节前移术(TTA)等胫骨近端截骨术却越来越普遍。本综述的目的是系统评价报告TPLO和TTA相关疗效及并发症的文献。

材料与方法

对文献数据库进行系统检索,确定2004年8月至2016年2月发表的描述TPLO或TTA短期或长期疗效以及并发症评估的文章。

结果

本综述纳入了91项研究,并分为四个证据水平中的一个。其中,89项研究提供了最低证据水平,只有两项被归为次优证据水平。主观步态分析的比较未发现TPLO和TTA在跛行减轻方面存在差异,而客观步态分析支持TPLO的优越性。接受TPLO治疗的患者术后关节不稳定的诊断较少,且TPLO术后骨关节炎(OA)的增加百分比更低。两种技术的主人满意度都很高。TPLO和TTA的平均总并发症率、轻微并发症率、严重并发症率和灾难性并发症率分别为15.9%和20.8%、7.9%和11.6%、5.2%和13.2%以及0.8%和5.6%。

结论及临床意义

评估的文献支持以下假设,即与TTA相比,TPLO的并发症发生率更低、临床功能结局更好且OA增加更少。结果表明TPLO术后肢体功能可长期恢复正常。然而,现有证据的强度以及各研究结果的可比性较差,需要更多的比较研究才能就TPLO相对于TTA的优越性得出有力结论。

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