Department of Emergency Medicine, Katip Çelebi University, Atatürk Training and Research Hospital, İzmir, Turkey.
Department of Emergency Medicine, Katip Çelebi University, Atatürk Training and Research Hospital, İzmir, Turkey.
Am J Emerg Med. 2018 Nov;36(11):2136.e1-2136.e2. doi: 10.1016/j.ajem.2018.08.054. Epub 2018 Aug 21.
Diabetic ketoacidosis (DKA) is a serious and potentially life-threatening acute complication of diabetes mellitus (DM). Sodium-glucose co-transporter-2(SGLT-2) inhibitors are new orally administered antihyperglycemic agents. These agents are related with rarely seen euglycemic diabetic ketoacidosis (eDKA) cases, which are difficult to diagnose in emergency department (ED) because of absence of an evident hyperglycemia and may result with potentially dangerous outcomes if missed. In this study, we present a clinical case of a patient, admitted to ED with altered mental status after SGLT2 inhibitor dapagliflozin administration.
糖尿病酮症酸中毒（DKA）是糖尿病（DM）的一种严重且潜在危及生命的急性并发症。钠-葡萄糖协同转运蛋白-2（SGLT-2）抑制剂是新型口服抗高血糖药物。这些药物与罕见的血糖正常性糖尿病酮症酸中毒（eDKA）病例有关，由于没有明显的高血糖，在急诊科（ED）难以诊断，并且如果漏诊可能会导致潜在的危险后果。在本研究中，我们报告了 1 例患者的临床病例，该患者在服用 SGLT2 抑制剂达格列净后因精神状态改变而被收入 ED。
