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前列腺腺癌肝转移,18F-胆碱摄取未见增高。

Hepatic Metastases From Prostatic Adenocarcinoma Without Elevated 18F-Choline Activity.

出版信息

Clin Nucl Med. 2018 Oct;43(10):780-781. doi: 10.1097/RLU.0000000000002254.

DOI:10.1097/RLU.0000000000002254
PMID:30153155
Abstract

We report the case of a 69-year-old man referred for F-fluorocholine (FCH) PET/CT for a biochemical recurrence of prostate cancer. FCH PET/CT demonstrated 2 hypodense hepatic lesions with no uptake but progressing in size compared with a previous assessment. MRI showed a suspicious peripheral contrast enhancement, raising the question of a liver metastasis. Histopathologic examination concluded to a prostate adenocarcinoma metastasis. This case highlights an unusual pitfall in FCH PET/CT: the lack of uptake in prostatic liver metastasis is presumably due to the partial volume effect induced by the necrotic center and the high uptake of the liver.

摘要

我们报告了一例 69 岁男性患者,因前列腺癌生化复发而行 F-氟胆碱(FCH)PET/CT 检查。FCH PET/CT 显示 2 个低密肝脏病灶,无摄取,但与之前的评估相比,病灶增大。MRI 显示可疑的周边对比增强,提示肝转移的可能性。组织病理学检查结果为前列腺腺癌转移。该病例强调了 FCH PET/CT 中一个不常见的陷阱:前列腺肝转移摄取不足可能是由于坏死中心引起的部分容积效应和肝脏摄取增加所致。

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