Department of Nephrology, Prince of Wales Hospital, Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
The School of Medicine, University of Queensland and The Department of Medicine, University of Otago, Christchurch, New Zealand.
Nephron. 2018;140(2):86-89. doi: 10.1159/000492290. Epub 2018 Aug 28.
While there are no clear definitions of recovery, it is clear that the goals of recovery depend on the severity of acute kidney injury and the clinical context. The degree of renal recovery affects both renal and clinical prognosis. There are presently few guidelines on recovery targets, which range in extent from dialysis independence via normalization of serum creatinine to recovery of renal functional reserve. However, while there are no validated biomarkers for predicting recovery, evidence suggests that both functional and damage biomarkers can aid the assessment of recovery.
虽然目前对于恢复并没有明确的定义，但很显然，恢复的目标取决于急性肾损伤的严重程度和临床背景。肾脏恢复的程度会影响肾脏和临床预后。目前，关于恢复目标的指南很少，范围从透析依赖到血清肌酐正常化，再到肾功能储备的恢复。然而，虽然目前还没有经过验证的生物标志物来预测恢复，但有证据表明，功能和损伤生物标志物都可以帮助评估恢复。
