体外成熟技术在多囊卵巢综合征/多囊卵巢中的地位
The Place of In Vitro Maturation in PCO/PCOS.
作者信息
Julania Shital, Walls Melanie L, Hart Roger
机构信息
King Edward Memorial Hospital, 374 Bagot Road, Subiaco, WA 6008, Australia.
Fertility North, Suite 213, Specialist Medical Centre, Joondalup Health Campus, Shenton Avenue, Joondalup, WA 6027, Australia.
出版信息
Int J Endocrinol. 2018 Jul 31;2018:5750298. doi: 10.1155/2018/5750298. eCollection 2018.
Abstract
In vitro maturation (IVM) of human oocytes is an emerging treatment option for women with polycystic ovary/polycystic ovary syndrome (PCO/PCOS) in addition to the standard in vitro fertilization (IVF) treatment. There has been significant improvements in pregnancy rates with IVM over the last two decades. This article reviews the place of IVM for women with PCO/PCOS, placing an emphasis on the predictors of successful pregnancy, optimization of culture media, IVM protocols, pregnancy rates, and neonatal outcomes following IVM treatment.
摘要
除了标准的体外受精（IVF）治疗外，人卵母细胞的体外成熟（IVM）是多囊卵巢/多囊卵巢综合征（PCO/PCOS）女性的一种新兴治疗选择。在过去二十年中，IVM的妊娠率有了显著提高。本文综述了IVM在PCO/PCOS女性中的地位，重点关注成功妊娠的预测因素、培养基的优化、IVM方案、妊娠率以及IVM治疗后的新生儿结局。
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An improved IVM method for cumulus-oocyte complexes from small follicles in polycystic ovary syndrome patients enhances oocyte competence and embryo yield.一种改良的多囊卵巢综合征患者小卵泡卵丘-卵母细胞复合物的玻璃化方法可提高卵母细胞成熟度和胚胎产量。
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