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类风湿关节炎患者的工作能力与就业情况:一项关于肌肉力量和下肢功能作用的横断面研究

Work Ability and Employment in Rheumatoid Arthritis: A Cross-Sectional Study on the Role of Muscle Strength and Lower Extremity Function.

作者信息

Berner Carolin, Haider Sandra, Grabovac Igor, Lamprecht Thomas, Fenzl Karl Heinrich, Erlacher Ludwig, Quittan Michael, Dorner Thomas Ernst

机构信息

Kaiser Franz Josef Hospital, Sozialmedizinisches Zentrum-Süd, Department of Rheumatology and Osteology, Vienna, Austria.

Karl Landsteiner Institute for Autoimmune Diseases and Rheumatology, Vienna, Austria.

出版信息

Int J Rheumatol. 2018 Aug 1;2018:3756207. doi: 10.1155/2018/3756207. eCollection 2018.

Abstract

OBJECTIVE

The aim of the present study was to assess the association between muscle strength, lower extremity function, employment status, and work ability in RA patients.

METHODS

One hundred seropositive RA outpatients of working age were included in this cross-sectional study. Employment status was assessed by interview and work ability by the Work Ability Index-Single Item Scale (WAS). Muscle strength was determined using dynamometer measurement of isometric hand grip and knee extensor strength. Lower extremity function was measured using the short physical performance battery (SPPB). Regression models estimate the association between unemployment, work ability and muscle strength, and lower extremity function, controlling for sociodemographic and disease-related factors.

RESULTS

Forty-one percent of the RA patients were not gainfully employed, and their median work ability had a good WAS value (7.00 [4.00-7.00]). Patients with better knee extensor strength (OR=1.07, 95% CI [1.02-1.12) and better physical performance (OR=1.71, 95% CI [1.18-2.49]) had a significantly better chance of gainful employment. The odds for hand grip strength remained significant when adjusted for sociodemographic (OR=1.5, 95% CI [1.00-1.09]), but not for disease-specific variables. Better hand grip strength (=0.25, =0.039) and better knee extensor strength (=0.45, =0.001) as well as better lower extremity function (SPPB) (=0.51, <0.001) remained significantly associated with work ability following adjustment for sociodemographic and disease-specific variables.

CONCLUSIONS

The association of employment status and work ability with parameters of physical fitness suggests that improvement in muscle strength and lower extremity function may positively influence work ability and employment in individuals with RA.

摘要

目的

本研究旨在评估类风湿关节炎(RA)患者的肌肉力量、下肢功能、就业状况和工作能力之间的关联。

方法

本横断面研究纳入了100名工作年龄的血清阳性RA门诊患者。通过访谈评估就业状况,使用工作能力指数单项量表(WAS)评估工作能力。使用测力计测量等长握力和膝关节伸肌力量来确定肌肉力量。使用简短体能测试电池(SPPB)测量下肢功能。回归模型估计失业、工作能力与肌肉力量以及下肢功能之间的关联,并对社会人口统计学和疾病相关因素进行控制。

结果

41%的RA患者没有从事有报酬的工作,他们的工作能力中位数具有良好的WAS值(7.00[4.00 - 7.00])。膝关节伸肌力量较好(OR = 1.07,95%CI[1.02 - 1.12])和体能较好(OR = 1.71,95%CI[1.18 - 2.49])的患者从事有报酬工作的机会明显更高。在对社会人口统计学因素进行调整后,握力的优势比仍然显著(OR = 1.5,95%CI[1.00 - 1.09]),但对疾病特异性变量进行调整后则不显著。在对社会人口统计学和疾病特异性变量进行调整后,较好的握力(β = 0.25,P = 0.039)、较好的膝关节伸肌力量(β = 0.45,P = 0.001)以及较好的下肢功能(SPPB)(β = 0.51,P < 0.001)与工作能力仍显著相关。

结论

就业状况和工作能力与身体素质参数之间的关联表明,肌肉力量和下肢功能的改善可能对RA患者的工作能力和就业产生积极影响。

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