犬巴贝斯虫病：临床并发症、生物标志物及治疗的概述
Canine babesiosis: a perspective on clinical complications, biomarkers, and treatment.
作者信息
Köster Liza S, Lobetti Remo G, Kelly Patrick
机构信息
Department of Clinical Sciences, One Health Center for Zoonoses and Tropical Veterinary Medicine, Ross University School of Veterinary Medicine, St Kitts, West Indies,
Bryanston Veterinary Hospital, Bryanston, South Africa.
出版信息
Vet Med (Auckl). 2015 Apr 10;6:119-128. doi: 10.2147/VMRR.S60431. eCollection 2015.
Abstract
Canine babesiosis is a common tick transmitted disease of dogs worldwide. A number of sp. can infect dogs and the spectrum is increasing as molecular methods are developed to differentiate organisms. Clinical signs are generally attributed to hemolysis caused by the organisms in the erythrocytes but in some animals with some spp. there can be an immune mediated component to the anemia and/or a severe inflammatory reaction associated. This complicated form of canine babesiosis is associated with high morbidity and mortality. A variety of clinical markers has been investigated to enable clinicians to provide more accurate prognoses and adapt their treatments which vary according to the infecting species. In this review, we discuss the taxonomy, clinical signs, diagnostic imaging, clinical biomarkers, treatment, and prophylaxis of one of the most common and important diseases of dogs worldwide.
摘要
犬巴贝斯虫病是一种在全球范围内常见的由蜱传播的犬类疾病。多种巴贝斯虫属物种可感染犬类，并且随着用于区分生物体的分子方法的发展，其种类范围正在扩大。临床症状通常归因于红细胞内生物体引起的溶血，但在一些感染某些物种的动物中，贫血可能存在免疫介导成分和/或伴有严重的炎症反应。这种复杂形式的犬巴贝斯虫病与高发病率和死亡率相关。人们已经研究了多种临床标志物，以使临床医生能够提供更准确的预后，并根据感染物种的不同调整治疗方法。在这篇综述中，我们讨论了全球范围内犬类最常见且最重要的疾病之一的分类学、临床症状、诊断影像学、临床生物标志物、治疗和预防。
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