Eberle Sarah, Dezoumbe Djeneba, McGregor Rhegan, Kinzer Shane, Raver Whitney, Schaack Sarah, Latta Leigh C
Lewis-Clark State College; Division of Natural Sciences and Mathematics; Lewiston, ID 83501.
Reed College; Department of Biology; Portland, OR 97202.
G3 (Bethesda). 2018 Nov 6;8(11):3481-3487. doi: 10.1534/g3.118.200472.
Understanding the context-dependence of spontaneous mutations is crucial to predicting evolutionary trajectories. In this experiment, the impact of genetic background and trait-type on mutational susceptibility was investigated. Mutant and non-mutant lines of six unique genotypes from two populations of were phenotypically assayed using a common-garden experiment. Morphological, life-history, and behavioral traits were measured and estimates of the mutation parameters were generated. The mutation parameters varied between the populations and among genotypes, suggesting differential susceptibility to mutation depending upon genomic background. Traits also varied in their susceptibility to mutation with behavioral traits evolving more rapidly than life-history and morphological traits. These results may reflect the unique selection histories of these populations.
了解自发突变的背景依赖性对于预测进化轨迹至关重要。在本实验中，研究了遗传背景和性状类型对突变敏感性的影响。使用共同花园实验对来自两个种群的六种独特基因型的突变系和非突变系进行了表型分析。测量了形态、生活史和行为性状，并生成了突变参数估计值。突变参数在种群之间和基因型之间有所不同，这表明根据基因组背景对突变的敏感性存在差异。性状对突变的敏感性也有所不同，行为性状的进化比生活史和形态性状更快。这些结果可能反映了这些种群独特的选择历史。
