Fahmy Alexander, MacDonald Gordon, Evans Alexander
Rheumatology, Royal Berkshire NHS Foundation Trust, 18 Wheeler Way, Basingstoke RG24 9TQ, UK.
Rheumatology, Royal Berkshire NHS Foundation Trust, Royal Berkshire Hospital, Reading RG1 5LE, UK.
Oxf Med Case Reports. 2018 Aug 25;2018(9):omy058. doi: 10.1093/omcr/omy058. eCollection 2018 Sep.
Abnormal liver function tests are often seen in patients with inflammatory arthritis. These are commonly associated with disease-modifying anti-rheumatic drugs, however, clinicians must hold a high index of suspicion for less common causes. This article details two of such cases where hereditary haemochromatosis and acute hepatitis E infection were actually responsible for deranged serum liver enzymes. Correct identification of these conditions leads to disease specific management and improved patient outcomes.
炎症性关节炎患者常出现肝功能检查异常。这些异常通常与改善病情抗风湿药物有关，然而，临床医生必须对不太常见的病因保持高度怀疑。本文详细介绍了两例病例，其中遗传性血色素沉着症和急性戊型肝炎感染实际上是血清肝酶紊乱的原因。正确识别这些病症可实现针对性治疗并改善患者预后。
