Wu Derek, Wasserman Jason, Boruk Marina
1 Department of Otolaryngology, SUNY Downstate Medical Center, Brooklyn, New York.
Am J Rhinol Allergy. 2018 Nov;32(6):485-490. doi: 10.1177/1945892418797056. Epub 2018 Aug 30.
The use of systemic corticosteroids remains controversial in the treatment of orbital complications of sinusitis.
To compare and contrast the current practice patterns of the use of systemic corticosteroid in the management of orbital complications of acute bacterial rhinosinusitis (ABRS) among fellowship-trained members of American Society of Pediatric Otolaryngology (ASPO) and American Rhinologic Society (ARS).
Cross-sectional survey.
A web-based survey was electronically distributed to 497 members of ASPO and 845 members of ARS focusing on the practice habits and opinions regarding the use of systemic corticosteroids in the treatment of ABRS with orbital complications in children and adults.
Survey completion rate was 19.1% among ASPO membership and 10.3% from ARS; 45% of respondents utilized steroids almost always or frequently in children and 36% of the time in adults. Most commonly reported indication for the use of steroid was vision change. Fellowship-trained pediatric otolaryngologists are 2.88 times more likely to prescribe corticosteroids for children than rhinologists ( P < .02). The perceived level of evidence in the literature was split between expert opinions and cohort studies.
In orbital complications of ABRS, practice patterns of the use of steroid differ significantly between fellowship-trained ASPO and ARS members with respect to its use in children. Overall, corticosteroids are administered with significant frequency, although there is little actual or perceived evidence to support their safety or efficacy. In alignment of practicing evidence-based medicine, further studies are needed to guide the use of steroids in complicated ABRS with respect to timing, dosing, route, duration, and indication.
全身使用糖皮质激素治疗鼻窦炎的眼眶并发症仍存在争议。
比较美国儿科耳鼻咽喉头颈外科学会(ASPO)和美国鼻科学会(ARS)中接受过专科培训的成员在治疗急性细菌性鼻-鼻窦炎(ABRS)眼眶并发症时使用全身糖皮质激素的当前实践模式。
横断面调查。
通过网络向497名ASPO成员和845名ARS成员进行电子问卷调查,重点关注在儿童和成人ABRS眼眶并发症治疗中使用全身糖皮质激素的实践习惯和观点。
ASPO成员的调查完成率为19.1%,ARS成员为10.3%;45%的受访者几乎总是或经常在儿童中使用类固醇,在成人中这一比例为36%。最常报告的使用类固醇的指征是视力改变。接受过专科培训的儿科耳鼻咽喉头颈外科医生给儿童开糖皮质激素的可能性是鼻科医生的2.88倍(P < 0.02)。文献中可感知的证据水平在专家意见和队列研究之间存在分歧。
在ABRS的眼眶并发症中,接受过专科培训的ASPO和ARS成员在儿童使用类固醇的实践模式上存在显著差异。总体而言,糖皮质激素的使用频率较高,尽管几乎没有实际或可感知的证据支持其安全性或有效性。为了践行循证医学,需要进一步研究以指导在复杂ABRS中使用类固醇的时机、剂量、途径、持续时间和指征。