Popova E V, Bryukhov V V, Boyko A N, Krotenkova M V
Interregional Department of Multiple Sclerosis at Moscow Clinical Hospital #24, Moscow, Russia; Pirogov Russian National Research Medical University, Moscow, Russia.
Research Center of Neurology, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(8. Vyp. 2):35-39. doi: 10.17116/jnevro201811808235.
The article presents a clinical case-report of transformation of radiologically isolated syndrome (RIS) to primary-progressive multiple sclerosis (PPMS). It also provides a review of international and Russian data on the comparison of clinical and MRI characteristics of PPMS with relapsing-remitting multiple sclerosis and secondary-progressive multiple sclerosis and the review of the current data on the risks of transition of RIS to PPMS.
本文介绍了一例放射学孤立综合征（RIS）转化为原发进展型多发性硬化症（PPMS）的临床病例报告。它还综述了国际和俄罗斯关于PPMS与复发缓解型多发性硬化症及继发进展型多发性硬化症临床和MRI特征比较的数据，以及关于RIS转化为PPMS风险的现有数据。
