[放射学孤立综合征作为原发进展型多发性硬化症可能的临床前期阶段]
[Radiologically isolated syndrome as a possible preclinical stage of primary-progressive multiple sclerosis].
作者信息
Popova E V, Bryukhov V V, Boyko A N, Krotenkova M V
机构信息
Interregional Department of Multiple Sclerosis at Moscow Clinical Hospital #24, Moscow, Russia; Pirogov Russian National Research Medical University, Moscow, Russia.
Research Center of Neurology, Moscow, Russia.
出版信息
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(8. Vyp. 2):35-39. doi: 10.17116/jnevro201811808235.
The article presents a clinical case-report of transformation of radiologically isolated syndrome (RIS) to primary-progressive multiple sclerosis (PPMS). It also provides a review of international and Russian data on the comparison of clinical and MRI characteristics of PPMS with relapsing-remitting multiple sclerosis and secondary-progressive multiple sclerosis and the review of the current data on the risks of transition of RIS to PPMS.
本文介绍了一例放射学孤立综合征（RIS）转化为原发进展型多发性硬化症（PPMS）的临床病例报告。它还综述了国际和俄罗斯关于PPMS与复发缓解型多发性硬化症及继发进展型多发性硬化症临床和MRI特征比较的数据，以及关于RIS转化为PPMS风险的现有数据。
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