1 Department of Radiology, The Children's Hospital of Philadelphia, 3NW39, 3401 Civic Center Blvd, Philadelphia, PA 19104.
2 Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
AJR Am J Roentgenol. 2018 Oct;211(4):910-919. doi: 10.2214/AJR.18.19712. Epub 2018 Aug 30.
The purpose of this article is to discuss approaches to imaging dysplasia epiphysealis hemimelica in the context of recent advances in the understanding of the underlying pathophysiologic profile of this entity, which may result in pain, growth disturbance, and early development of osteoarthritis.
Dysplasia epiphysealis hemimelica was first characterized as a skeletal disorder with osteochondromas characteristically involving epiphyses on one side of the same lower extremity. Upper extremity involvement was subsequently recognized. Previously conceptualized as epiphyseal osteochondromatosis, recent investigations have uncovered differences between these osteocartilaginous lesions and osteochondromas.
本文旨在讨论在对该实体潜在病理生理特征的理解不断深入的背景下,探讨骺板发育不良性半肢肥大症的影像学方法,因为这可能导致疼痛、生长障碍和早期骨关节炎的发生。
骺板发育不良性半肢肥大症最初被认为是一种骨骼疾病,其特征是同侧下肢的骺软骨瘤典型地累及骺。随后认识到上肢也会受累。既往被认为是骺软骨瘤病,最近的研究揭示了这些软骨-骨病变与软骨瘤之间的差异。