Green Calvin, Moore Christine Ann, Mahajan Akhilesh, Bajaj Kailash
Department of Internal Medicine, East Tennessee State University James H. Quillen College of Medicine, Johnson City, TN, USA.
J Glob Infect Dis. 2018 Jul-Sep;10(3):159-162. doi: 10.4103/jgid.jgid_88_17.
is a bacterium responsible for a spectrum of diseases including lobar pneumonia, meningitis, otitis media, and sinusitis. Invasive pneumococcal disease is responsible for significant morbidity and mortality across the world. Concerted efforts led to the development of two vaccinations, Pneumova × 23 and Prevnar 13, for the prevention of pneumococcal disease. The Advisory Committee on Immunization Practices of the US Centers for Disease Control and Prevention provides vaccination schedules for predisposed adults, but the proposed schedules remain a challenge to health-care providers. We performed a systematic review in PubMed and these specialty group websites to present the pathophysiology of pneumococcal disease, outline different pneumococcal vaccinations, and condense recommendations for vaccination administration.
是一种可导致多种疾病的细菌，包括大叶性肺炎、脑膜炎、中耳炎和鼻窦炎。侵袭性肺炎球菌疾病在全球范围内导致了显著的发病率和死亡率。共同努力促成了两种预防肺炎球菌疾病的疫苗的研发，即23价肺炎球菌多糖疫苗（Pneumova × 23）和13价肺炎球菌结合疫苗（Prevnar 13）。美国疾病控制与预防中心免疫实践咨询委员会为易感成年人提供了疫苗接种时间表，但拟议的时间表对医疗保健提供者来说仍是一项挑战。我们在PubMed和这些专业组织网站上进行了系统综述，以阐述肺炎球菌疾病的病理生理学，概述不同的肺炎球菌疫苗，并归纳疫苗接种管理的建议。
