Okamura Takeshi, Beppu Takeshi, Tokumaru Takao, Yamada Masato, Sugiyama Tomonori, Koide Nobuaki, Tani Miyuki, Kaneko Masayuki, Hamahata Atsumori, Nishimura Yu, Fukuda Takashi
Department of Head and Neck Surgery, Saitama Cancer Center, Saitama, Japan.
Department of Head and Neck Surgery, Saitama Cancer Center, Saitama, Japan.
Auris Nasus Larynx. 2019 Jun;46(3):479-482. doi: 10.1016/j.anl.2018.08.006. Epub 2018 Aug 28.
Head and neck cancer metastasizing to the small intestine is very rare. Here we report a case of cancer of the mandibular gingiva metastasizing to the small intestine. The patient was an 82-year-old man who had squamous cell carcinoma of the mandibular gingiva staged as T2N2bM0. Two months after surgery, he presented with lower abdominal pain accompanied by signs of peritoneal irritation. Urgent abdominal surgery was performed, during which a crater-shaped perforation was noted on the wall of the ileum. Microscopic findings at this site confirmed a diagnosis of metastatic squamous cell carcinoma in the small intestine from the mandibular gingiva. To our knowledge, this is the first case report of oral cancer metastasizing to the small intestine. If gastrointestinal symptoms appear in a patient with advanced oral cancer, a differential diagnosis of metastasis to the gastrointestinal tract should be kept in mind.
头颈部癌转移至小肠极为罕见。在此，我们报告一例下颌牙龈癌转移至小肠的病例。患者为一名82岁男性，下颌牙龈鳞状细胞癌分期为T2N2bM0。术后两个月，他出现下腹部疼痛并伴有腹膜刺激征。遂进行急诊腹部手术，术中发现回肠壁有一个火山口状穿孔。该部位的显微镜检查结果证实为下颌牙龈癌转移至小肠的鳞状细胞癌。据我们所知，这是口腔癌转移至小肠的首例病例报告。如果晚期口腔癌患者出现胃肠道症状，应考虑到胃肠道转移的鉴别诊断。
