Taira T, Amano K, Kawamura H, Tanikawa T, Kitamura K
Appl Neurophysiol. 1985;48(1-6):267-70. doi: 10.1159/000101139.
The authors recorded cerebral-evoked responses elicited by direct stimulation of the human lateral spinothalamic tract (LST) during percutaneous cordotomy to investigate central conduction of noxious stimuli. These responses consisted of four negative potentials, peak latency being 3.8 (N1), 8.4 (N2), 12.2 (N3) and 21.9 (N4) ms respectively. N1 showed wide distribution over the scalp and was considered to be of subcortical origin. N2-N4 were distributed in both the temporal and central area. The different distribution pattern of N2-N4 from conventional somatosensory-evoked potential suggested a different projection of LST from the medial lemniscus system.
作者在经皮脊髓切断术期间记录了直接刺激人类外侧脊髓丘脑束(LST)所引发的脑诱发反应,以研究伤害性刺激的中枢传导。这些反应由四个负电位组成,其峰值潜伏期分别为3.8(N1)、8.4(N2)、12.2(N3)和21.9(N4)毫秒。N1在头皮上分布广泛,被认为起源于皮层下。N2 - N4分布于颞区和中央区。N2 - N4与传统体感诱发电位不同的分布模式表明LST与内侧丘系系统的投射不同。