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青少年不明原因猝死(SUDEP)的尸检结果。

Autopsy findings of SUDEP in adolescence.

作者信息

Afandi D, Romus I

机构信息

Universitas Riau, Faculty of Medicine, Forensic Medicine and Medicolegal Studies Department, Jl. Diponegoro 1, Pekanbaru, Riau, Indonesia.

出版信息

Malays J Pathol. 2018 Aug;40(2):185-189.

Abstract

Sudden unexpected death in epilepsy (SUDEP) is a rare in children; the risk of SUDEP in children is up to 10-fold less than adults. Herein, we report a case of SUDEP in a 14-year-old boy. The post-mortem findings in neuropathological examination in SUDEP are not pathognomonic. Tongue and lip bites marks are only an indication of a seizure before death. Basically, there are no lesions that could explain the incidence of seizures before death. However, post-mortem examination is mandatory in order to determine the diagnosis of SUDEP. Autopsy, histopathological, and toxicologic examinations and a proper medical history of epilepsy are required to come to diagnosis of SUDEP. This case report further demonstrates the importance of medicolegal autopsy in allegedly dead victims.

摘要

癫痫猝死(SUDEP)在儿童中较为罕见;儿童发生SUDEP的风险比成人低至十分之一。在此,我们报告一例14岁男孩的SUDEP病例。SUDEP尸检的神经病理学检查结果并无特异性。舌部和唇部咬伤痕迹仅表明死前曾发生癫痫发作。基本上,没有病变能够解释死前癫痫发作的情况。然而,尸检对于确定SUDEP的诊断是必不可少的。诊断SUDEP需要进行尸体解剖、组织病理学和毒理学检查以及详细的癫痫病史。本病例报告进一步证明了法医学尸检在疑似死亡受害者中的重要性。

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