Dima-Cozma Lucia Corina, Bitere Oana Roxana, Pantazescu Adrian Nicolae, Gologan Elena, Mitu Florin, Rădulescu Doiniţa, Cozma Romică Sebastian
Department of Otorhinolaryngology, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iaşi, Romania;
Rom J Morphol Embryol. 2018;59(2):557-561.
Hemangiomas, the most common benign tumors of the liver, have a prevalence of approximately 20% and are more frequent in women. According to previous studies, the size and location of the tumor are correlated with the appearance of symptoms and complications. Cases of hemangiomas complicated by spontaneous intratumoral hemorrhage have been rarely reported in the literature. Here, we report the case of a 70-year-old woman admitted for persistent upper abdominal pain. The patient showed signs of anemia, inflammatory markers and a transient increase in creatinine levels, which were corrected by conservative treatment. Our patient denied the previous use of estrogen derivatives, smoking or alcohol consumption. Native computed tomography identified a liver mass measuring 73×63 mm, located in segment IV and bulging out of the anterior contour of the liver. The mass was surgically removed by hepatic segmentectomy, and histopathological examination identified a cavernous hemangioma complicated by intratumoral hemorrhage. The postoperative outcome was favorable. After a literature review, we identified 19 other cases of hepatic cavernous hemangioma complicated by intratumoral hemorrhage reported worldwide.
肝血管瘤是肝脏最常见的良性肿瘤，患病率约为20%，在女性中更为常见。根据以往的研究，肿瘤的大小和位置与症状及并发症的出现相关。肝血管瘤并发自发性瘤内出血的病例在文献中鲜有报道。在此，我们报告一例因持续性上腹痛入院的70岁女性病例。患者出现贫血迹象、炎症标志物升高以及肌酐水平短暂升高，经保守治疗后恢复正常。我们的患者否认既往使用过雌激素衍生物、吸烟或饮酒。肝脏计算机断层扫描发现一个大小为73×63 mm的肝脏肿块，位于肝IV段，从肝脏前缘突出。该肿块通过肝段切除术手术切除，组织病理学检查确诊为伴有瘤内出血的海绵状肝血管瘤。术后结果良好。经文献检索，我们在全球范围内又发现了19例肝海绵状血管瘤并发瘤内出血的病例。
