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采用高剂量率近距离放射疗法和外照射治疗足部广泛性皮肤T细胞淋巴瘤

Extensive Cutaneous T-Cell Lymphoma of the Feet Treated with High-Dose-Rate Brachytherapy and External Beam Radiation.

作者信息

Tao Joy, Hentz Courtney, Mysz Michael L, Rashed Issra, Eilers David, Swan James, Tung Rebecca, Emami Bahman

机构信息

Stritch School of Medicine, Loyola University Chicago, Chicago, IL, USA.

Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Chicago, IL, USA.

出版信息

Case Rep Dermatol Med. 2018 Aug 7;2018:5610925. doi: 10.1155/2018/5610925. eCollection 2018.

Abstract

Cutaneous T-cell lymphoma (CTCL) is a chronic, debilitating disease that has a severe impact on quality of life. We present a patient with multiple CTCL lesions on the bilateral feet, which impaired his ability to ambulate. His lesions on both feet were successfully treated with a total of 8 Gy in two fractions via high-dose-rate surface brachytherapy using the Freiburg Flap applicator. The deeper aspects of the bulkier lesions on the left foot were boosted with electron beam therapy. The radiation therapy was well tolerated, and the patient was able to regain his mobility after completing radiation therapy. To our knowledge, there are few reports utilizing brachytherapy in treating CTCL. Our case describes treatment of larger, more extensive CTCL lesions than previously reported.

摘要

皮肤T细胞淋巴瘤(CTCL)是一种慢性、使人衰弱的疾病,对生活质量有严重影响。我们报告一名患者,其双脚有多处CTCL病变,影响了他的行走能力。通过使用弗莱堡皮瓣施源器进行高剂量率表面近距离放射治疗,分两次共给予8 Gy的剂量,成功治疗了他双脚的病变。左脚较大肿块病变的深部区域采用电子束治疗进行增强照射。放射治疗耐受性良好,患者在完成放射治疗后能够恢复行动能力。据我们所知,很少有关于使用近距离放射治疗CTCL的报道。我们的病例描述了比以往报道更大、更广泛的CTCL病变的治疗情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4903/6106951/88b83ddc47d2/CRIDM2018-5610925.001.jpg

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