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"Splice" a way towards neuroendocrine prostate cancer.

作者信息

Zhang Dingxiao, Tang Dean G

机构信息

Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA; Key Lab of Agricultural Animal Genetics and Breeding, Ministry of Education, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.

Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.

出版信息

EBioMedicine. 2018 Sep;35:12-13. doi: 10.1016/j.ebiom.2018.08.037. Epub 2018 Aug 31.

DOI:10.1016/j.ebiom.2018.08.037
PMID:30177243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6161471/
Abstract
摘要

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A novel mechanism of SRRM4 in promoting neuroendocrine prostate cancer development via a pluripotency gene network.一种新型的 SRRM4 机制，通过多能性基因网络促进神经内分泌前列腺癌的发展。
EBioMedicine. 2018 Sep;35:167-177. doi: 10.1016/j.ebiom.2018.08.011. Epub 2018 Aug 10.
2
Cancer stem cells: Regulation programs, immunological properties and immunotherapy.癌症干细胞：调控程序、免疫特性和免疫疗法。
Semin Cancer Biol. 2018 Oct;52(Pt 2):94-106. doi: 10.1016/j.semcancer.2018.05.001. Epub 2018 May 9.
3
Development of Neuroendocrine Prostate Cancers by the Ser/Arg Repetitive Matrix 4-Mediated RNA Splicing Network.丝氨酸/精氨酸重复基质4介导的RNA剪接网络在神经内分泌前列腺癌发生中的作用
Front Oncol. 2018 Apr 3;8:93. doi: 10.3389/fonc.2018.00093. eCollection 2018.
4
Histone 2B-GFP Label-Retaining Prostate Luminal Cells Possess Progenitor Cell Properties and Are Intrinsically Resistant to Castration.组蛋白 2B-GFP 标记保留前列腺腔细胞具有祖细胞特性，并对去势具有内在抗性。
Stem Cell Reports. 2018 Jan 9;10(1):228-242. doi: 10.1016/j.stemcr.2017.11.016. Epub 2017 Dec 21.
5
Establishment of a neuroendocrine prostate cancer model driven by the RNA splicing factor SRRM4.由RNA剪接因子SRRM4驱动的神经内分泌前列腺癌模型的建立
Oncotarget. 2017 Aug 3;8(40):66878-66888. doi: 10.18632/oncotarget.19916. eCollection 2017 Sep 15.
6
Emerging Variants of Castration-Resistant Prostate Cancer.去势抵抗性前列腺癌的新兴变体
Curr Oncol Rep. 2017 May;19(5):32. doi: 10.1007/s11912-017-0593-6.
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Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors that Can Function as a Cell of Origin for Prostate Cancer.开发一种新型的二维培养体系来富集人前列腺管腔祖细胞，使其能够作为前列腺癌的起始细胞。
Stem Cells Transl Med. 2017 Mar;6(3):748-760. doi: 10.5966/sctm.2016-0243. Epub 2016 Sep 29.
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SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer.SOX2促进TP53和RB1缺陷型前列腺癌中的谱系可塑性和抗雄激素耐药性。
Science. 2017 Jan 6;355(6320):84-88. doi: 10.1126/science.aah4307.
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Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance.Rb1和Trp53协同作用以抑制前列腺癌的谱系可塑性、转移和抗雄激素耐药性。
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