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奶山羊的长蝽:繁殖季节期间评估的超声变量和治疗方案

Hydrometra in dairy goats: Ultrasonic variables and therapeutic protocols evaluated during the reproductive season.

作者信息

Maia A L R S, Brandão F Z, Souza-Fabjan J M G, Veiga M O, Balaro M F A, Siqueira L G B, Facó O, Fonseca J F

机构信息

Faculdade de Veterinária, Universidade Federal Fluminense, Av. Vital Brazil Filho, 64, CEP 24230-340, Niterói, RJ, Brazil.

Faculdade de Veterinária, Universidade Federal Fluminense, Av. Vital Brazil Filho, 64, CEP 24230-340, Niterói, RJ, Brazil.

出版信息

Anim Reprod Sci. 2018 Oct;197:203-211. doi: 10.1016/j.anireprosci.2018.08.030. Epub 2018 Aug 26.

Abstract

Hydrometra is characterized by the accumulation of fluid within the uterus due to the persistence of corpus luteum. The diagnosis of this disorder occurs with an ultrasonic exam. This study evaluated uterine drainage and fertility rates in goats after the use of d-cloprostenol in association or not with Gonadotropin-releasing hormone (GnRH) treatment. Twenty Saanen goats, diagnosed with hydrometra, received three 37.5-μg doses of d-cloprostenol laterovulvarly at 10-day intervals. On D5, the goats were assigned into two groups receiving 1 mL of GnRH or saline solution intramuscularly. Ultrasonography (US) was performed from D0 to D25. An US approach was used to rank hydrometra in scores. The pregnancy rate was assessed 45 and 90 days after the end of treatment. The uterine fluid was totally drained after the first and second administration of d-cloprostenol in 50% and 95% of the goats, respectively. In one female, full emptying of the uterus occurred only after D20. US performed at 45 and 90 days after the end of treatment indicated there was a pregnancy rate of 45.0% and 55.0%, respectively. Fertility did not differ between the GnRH-treated and control goats. Those goats not pregnant at 45 days had a follicular cyst, hydrosalpinx or hydrometra. At 90 days, no change was observed in the hydrosalpinx, and four goats had hydrometra. The use of three doses of d-cloprostenol 10 days apart was efficient for induction of draining the contents of the uterus, resulting in a relatively acceptable pregnancy rate. This treatment associated with the US approach can be important when applied in the field.

摘要

积水性子宫是由于黄体持续存在导致子宫内积液。这种病症通过超声检查进行诊断。本研究评估了在使用氯前列醇(d - cloprostenol)联合或不联合促性腺激素释放激素(GnRH)治疗后山羊的子宫排液情况和受孕率。二十只被诊断为积水性子宫的萨能山羊,每隔10天从外阴侧给予三次37.5μg剂量的氯前列醇。在第5天,将山羊分为两组,分别肌肉注射1mL GnRH或生理盐水。从第0天到第25天进行超声检查(US)。采用超声方法对积水性子宫进行评分。在治疗结束后45天和90天评估受孕率。分别有50%和95%的山羊在首次和第二次注射氯前列醇后子宫积液完全排出。在一只母羊中,子宫直到第20天后才完全排空。治疗结束后45天和90天进行的超声检查表明,受孕率分别为45.0%和55.0%。GnRH治疗组和对照组山羊的生育能力没有差异。在45天时未怀孕的山羊存在卵泡囊肿、输卵管积水或积水性子宫。在90天时,输卵管积水情况未观察到变化,有四只山羊存在积水性子宫。每隔10天使用三次氯前列醇对诱导子宫内容物排出有效,从而产生相对可接受的受孕率。这种与超声方法相结合的治疗方法在实际应用中可能很重要。

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