Hesselink J W
Veterinary Clinic Marum, The Netherlands.
Vet Rec. 1993 Aug 21;133(8):186-7. doi: 10.1136/vr.133.8.186.
An intramuscular injection of 5 mg dinoprost caused a discharge of uterine fluid (cloudburst) in 49 cases of hydrometra in goats during the breeding seasons of 1988, 1989 and 1990. A spontaneous oestrus after the cloudburst was allowed to occur in 20 of the goats; in nine (45 per cent) of them a hydrometra recurred, three conceived at the first oestrus and eight returned to oestrus. Oestrus was induced in 29 other cases by means of a second intramuscular administration of 5 mg dinoprost, 12 days after the cloudburst. In this group a hydrometra recurred in only one goat, 14 goats (48 per cent) conceived at the first oestrus and 14 returned to oestrus. Of the animals in which a pseudopregnancy occurred once or more during the same breeding season, 85 per cent became pregnant, compared with 97 per cent of unaffected older goats. The mean number of kids of the goats that became pregnant and kidded after treatment for hydrometra was 2.0 compared with 2.3 for unaffected animals. The results indicate that a single administration of prostaglandin is not a satisfactory therapy for a hydrometra, but that reproductive performance improves when a second injection is given 12 days after the cloudburst.
1988年、1989年和1990年繁殖季节期间，对49例山羊积水性子宫积脓进行肌内注射5毫克地诺前列素，引发子宫排液（倾盆大雨般）。倾盆大雨般排液后，20只山羊出现自发发情；其中9只（45%）再次出现积水性子宫积脓，3只在首次发情时受孕，8只再次发情。倾盆大雨般排液12天后，对另外29例进行第二次肌内注射5毫克地诺前列素诱导发情。该组中仅1只山羊再次出现积水性子宫积脓，14只山羊（48%）在首次发情时受孕，14只再次发情。在同一繁殖季节发生一次或多次假孕的动物中，85%怀孕，而未受影响的老年山羊为97%。积水性子宫积脓治疗后怀孕并产仔的山羊平均产仔数为2.0只，未受影响的动物为2.3只。结果表明，单次注射前列腺素并非治疗积水性子宫积脓的满意疗法，但倾盆大雨般排液12天后进行第二次注射可改善繁殖性能。
