冠状动脉旁路移植术后大隐静脉移植物病变的危险因素、治疗及预防综述
Review of risk factors, treatment, and prevention of saphenous vein graft disease after coronary artery bypass grafting.
作者信息
Gao Jing, Liu Yin, Li Yu-Ming
机构信息
1 Logistics University of Chinese People's Armed Police Forces, Dongli District, Tianjin, P. R. China.
2 Cardiovascular Institute, Tianjin Chest Hospital, Jinnan District, Tianjin, P. R. China.
出版信息
J Int Med Res. 2018 Dec;46(12):4907-4919. doi: 10.1177/0300060518792445. Epub 2018 Sep 4.
Abstract
Saphenous vein graft disease (SVGD) is a type of vascular disease that may develop after coronary artery bypass grafting (CABG). SVGD seriously affects the short-term and long-term effects of CABG and increases the incidence of major adverse cardiovascular events. It is very important to identify patients at greatest risk and carry out prevention and treatment measures to determine the risk factors for SVGD. Many factors contribute to SVGD when the vein is grafted into an arterial environment, such as surgery-related factors, smoking, diabetes mellitus, hyperlipidemia, and others. In this review, we discuss the risk factors for SVGD, current surgical and pharmacologic therapies with which to manage SVGD, and the prevention of SVGD.
摘要
大隐静脉移植血管病变（SVGD）是一种可能在冠状动脉旁路移植术（CABG）后发生的血管疾病。SVGD严重影响CABG的短期和长期效果，并增加主要不良心血管事件的发生率。识别风险最高的患者并采取预防和治疗措施以确定SVGD的危险因素非常重要。当静脉移植到动脉环境中时，许多因素会导致SVGD，如手术相关因素、吸烟、糖尿病、高脂血症等。在本综述中，我们讨论了SVGD的危险因素、目前用于治疗SVGD的手术和药物疗法以及SVGD的预防。
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