Bhatt Anusha S, Babu D Nagendra, Sivakoti Sumitra, Teegala Ramesh, Mahadevan Anita
Clin Neuropathol. 2018 Nov/Dec;37(6):288-291. doi: 10.5414/NP301114.
Chondroblastomas are benign tumors of the osteoarticular system, involving long bones of skeletally immature individuals. Chondroblastomas of skull and facial bones are rare, with a predilection for temporal bone. We report the second case of chondroblastoma of frontal bone in world literature in an 8-year-old boy who presented with a painless swelling on the left side of the forehead increasing in size over 1 year. Plain radiography of the skull revealed a circular punched-out lesion in the left frontal precoronal area. Histopathology of the tumor on complete excision showed features of chondroblastoma with increased proliferation. The tumor cells coexpressed vimentin and S100. Complete excision is the recommended treatment with close follow-up for early diagnosis of recurrence. .
软骨母细胞瘤是骨-关节系统的良性肿瘤，累及骨骼未成熟个体的长骨。颅骨和面部骨骼的软骨母细胞瘤罕见，好发于颞骨。我们报告世界文献中第二例额骨软骨母细胞瘤，患者为一名8岁男孩，左侧前额出现无痛性肿胀，1年内逐渐增大。颅骨平片显示左额前冠状区域有一个圆形的穿凿样病变。肿瘤完整切除后的组织病理学检查显示具有增殖增加的软骨母细胞瘤特征。肿瘤细胞共表达波形蛋白和S100。推荐的治疗方法是完整切除，并密切随访以便早期诊断复发。
