Chaudhry Muhammad Ali, Grazette Luanda, Yoon Andrew, Correa Adrian, Fong Michael W
Division of Cardiovascular Medicine, Aultman Hospital, Canton, Ohio-44710 OH, United States.
Division of Cardiovascular Medicine, University of Southern California, Los Angeles-90033 CA, United States.
Curr Hypertens Rev. 2019;15(1):8-12. doi: 10.2174/1573402114666180903164900.
Acute eosinophilic myocarditis (EM) is a rare form of heart failure that is characterized by myocardial eosinophilic infiltration usually in association with peripheral eosinophilia. The underlying cause is variable and can include allergic reactions, parasitic infection, idiopathic hypereosinophilic syndrome, malignancy, Loeffler's syndrome, Churg-Strauss syndrome (CSS), early giant cell myocarditis and malignancy. The course is potentially fatal, and early diagnosis and treatment with steroids is essential.
Here, we present an illustrative case of eosinophilic myocarditis secondary to CSS followed by a brief review of epidemiology, pathogenesis, diagnosis and treatment of both disease entities.
急性嗜酸性粒细胞性心肌炎(EM)是一种罕见的心力衰竭形式,其特征是心肌嗜酸性粒细胞浸润,通常伴有外周嗜酸性粒细胞增多。潜在病因多种多样,可包括过敏反应、寄生虫感染、特发性高嗜酸性粒细胞综合征、恶性肿瘤、吕弗勒综合征、变应性肉芽肿性血管炎(CSS)、早期巨细胞心肌炎和恶性肿瘤。该病病情可能致命,早期诊断并使用类固醇治疗至关重要。
在此,我们展示一例继发于CSS的嗜酸性粒细胞性心肌炎病例,并简要回顾这两种疾病的流行病学、发病机制、诊断和治疗。