原发性干燥综合征中趋化因子受体 4 的表达。

Chemokine Receptor 4 Expression in Primary Sjögren's Syndrome.

机构信息

Institute of Pathology, University of Würzburg, Comprehensive Cancer Center Mainfranken (CCCMF), Würzburg, Germany.

Nagasaki University, School of Medicine, Nagasaki, Japan.

出版信息

Clin Nucl Med. 2018 Nov;43(11):835-836. doi: 10.1097/RLU.0000000000002258.

DOI:10.1097/RLU.0000000000002258

PMID:30179908

Abstract

Ga-pentixafor is a novel radioligand of C-X-C motif chemokine receptor 4. A 55-year-old woman with a history of primary Sjögren's syndrome underwent Ga-pentixafor PET/CT for staging of lymphoma originating from mucosa-associated lymphoid tissue. Whereas no lymphoma manifestation could be detected, imaging revealed bilateral intense radiotracer uptake in both parotid and submandibular salivary glands, consistent with inflammatory cell infiltration.

摘要

加喷他西林是一种新型 C-X-C 基序趋化因子受体 4 的放射性配体。一名 55 岁女性，既往原发性干燥综合征病史，因黏膜相关淋巴组织起源的淋巴瘤行 Ga-喷他西林 PET/CT 分期。虽然未发现淋巴瘤表现，但影像学显示双侧腮腺和颌下腺均有强烈的放射性示踪剂摄取，符合炎症细胞浸润。