School of Mechanical Engineering and Automation , Beihang University , Beijing 100191 , China.
Department of Bioengineering and Therapeutic Sciences , University of California , San Francisco , California 94158 , United States.
ACS Appl Mater Interfaces. 2018 Oct 3;10(39):33713-33720. doi: 10.1021/acsami.8b13373. Epub 2018 Sep 19.
Electrosurgery based on electrosurgical instruments plays an important role in clinical surgery owing to its advantages of ease of operation, low damage, and less pain to the patient. But soft tissue adhesion on electrosurgical instruments is still a major obstacle to improve the operation efficiency and achieve a better surgical result, regardless of so many developed methods to enhance the antiadhesion performance. In this paper, we successfully demonstrated that liquid-infused surfaces (LISs) can significantly improve the antiadhesion performance of electrosurgical instruments. We developed a microcontact printing method to assist the structure fabrication on the small instrument tip to prepare a firmly liquid-held surface. Soft tissue cutting experiments showed that LIS could not only significantly reduce the adhesion force between the tissue and the instrument tip but also lead to a much smaller charring wound. The underlying mechanism was discussed, and further experiments concluded that LIS have a better duration capability. Our study provides a new insight into the antiadhesion design for electrosurgical instruments.
基于电外科器械的电外科在临床手术中起着重要作用，其具有操作简便、损伤小、患者痛苦少等优点。但是，无论采用了多少种提高抗粘连性能的先进方法，电外科器械上的软组织粘连仍然是提高手术效率和实现更好手术效果的主要障碍。在本文中，我们成功地证明了液体浸润表面（LIS）可以显著提高电外科器械的抗粘连性能。我们开发了一种微接触印刷方法来辅助结构在小器械尖端上的制造，以制备牢固的液体保持表面。软组织切割实验表明，LIS 不仅可以显著降低组织与器械尖端之间的粘附力，而且还会导致较小的焦痂伤口。讨论了其潜在的机制，进一步的实验得出结论，LIS 具有更好的耐久性。我们的研究为电外科器械的抗粘连设计提供了新的思路。
