Department of Anesthesiology, Thomas Jefferson University Hospital, Philadelphia, PA, United States of America. Author to whom any correspondence should be addressed. 1020 Locust Street, Philadelphia, PA 19107, United States of America.
Physiol Meas. 2018 Sep 27;39(9):098001. doi: 10.1088/1361-6579/aadf11.
A recent study investigated the potential utility of new photoplethysmogram (PPG) indicators to improve cuffless continuous blood pressure (BP) measurement.
In this Comment we provide additional discussion of the physiology underlying PPG- and pulse arrival time (PAT)-based BP measurement. We also discuss validation of these measurements.
Changes in PPG features and PAT can occur independently of BP. Any study validating BP measurement based on PPG features or PAT should include a variety of calibration independent physiological challenges affecting BP.
PPG/PAT-based BP measurement has been investigated extensively as an alternative to cuff-based BP measurement. We feel the inherent physiological confounding in PPG/PAT-based measurement makes it unlikely that it will be of clinical value.
最近的一项研究调查了新的光体积描记图（PPG）指标在改善无袖带连续血压（BP）测量中的潜在应用。
在本评论中，我们提供了对 PPG 和脉搏到达时间（PAT）基础 BP 测量的生理学基础的更多讨论。我们还讨论了这些测量的验证。
PPG 特征和 PAT 的变化可以独立于 BP 发生。任何验证基于 PPG 特征或 PAT 的 BP 测量的研究都应包括各种影响 BP 的独立于校准的生理挑战。
基于 PPG/PAT 的 BP 测量已被广泛研究作为基于袖带的 BP 测量的替代方法。我们认为，基于 PPG/PAT 的测量中固有的生理混淆使得它不太可能具有临床价值。
