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心脏骤停及心肺复苏联合被动氧合/通气期间的动脉血气变化:一项METI HPS研究

Arterial blood gas changes during cardiac arrest and cardiopulmonary resuscitation combined with passive oxygenation/ventilation: a METI HPS study.

作者信息

Strnad Matej, Lešnik Damjan, Križmarić Miljenko

机构信息

1 Medical Faculty, University of Maribor, Maribor, Slovenia.

2 Faculty of Health Sciences, University of Maribor, Maribor, Slovenia.

出版信息

J Int Med Res. 2018 Nov;46(11):4605-4616. doi: 10.1177/0300060518786916. Epub 2018 Sep 5.

Abstract

OBJECTIVE

High-fidelity simulators can simulate physiological responses to medical interventions. The dynamics of the partial arterial pressure of oxygen (PO), partial arterial pressure of carbon dioxide (PCO), and oxygen pulse saturation (SpO) during simulated cardiopulmonary resuscitation (CPR) were observed and compared with the results from the literature.

METHODS

Three periods of cardiac arrest were simulated using the METI Human Patient Simulator™ (Medical Education Technologies, Inc., Sarasota, FL, USA): cardiac arrest, chest compression-only CPR, and chest compression-only CPR with continuous flow insufflation of oxygen (CFIO).

RESULTS

In the first period, the observed values remained constant. In the second period, PCO started to rise and peaked at 63.5 mmHg. In the CFIO period, PCO slightly fell. PO and SO declined only in the second period, reaching their lowest values of 44 mmHg and 70%, respectively. In the CFIO period, PO began to rise and peaked at 614 mmHg. SO exceeded 94% after 2 minutes of CFIO.

CONCLUSIONS

The METI Human Patient Simulator™ accurately simulated the dynamics of changes in PCO. Use of this METI oxygenation model has some limitations because the simulated levels of PO and SO during cardiac arrest correlate poorly with the results from published studies.

摘要

目的

高保真模拟器可模拟对医疗干预的生理反应。观察了模拟心肺复苏(CPR)期间动脉血氧分压(PO)、动脉血二氧化碳分压(PCO)和氧脉搏饱和度(SpO)的动态变化,并与文献结果进行比较。

方法

使用METI人体患者模拟器™(美国佛罗里达州萨拉索塔市Medical Education Technologies公司)模拟三个心脏骤停阶段:心脏骤停、单纯胸外按压心肺复苏和单纯胸外按压并持续气流给氧(CFIO)的心肺复苏。

结果

在第一阶段,观察值保持恒定。在第二阶段,PCO开始上升,峰值为63.5 mmHg。在CFIO阶段,PCO略有下降。PO和SO仅在第二阶段下降,分别降至最低值44 mmHg和70%。在CFIO阶段,PO开始上升,峰值为614 mmHg。CFIO 2分钟后,SO超过94%。

结论

METI人体患者模拟器™准确模拟了PCO的动态变化。该METI氧合模型的使用存在一些局限性,因为心脏骤停期间模拟的PO和SO水平与已发表研究的结果相关性较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6be/6259407/be7ccb1689b1/10.1177_0300060518786916-fig1.jpg

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