Lasinski Alaina M, Gil Lindsay, Kothari Anai N, Anstadt Michael J, Gonzalez Richard P
Am Surg. 2018 Aug 1;84(8):1288-1293.
Previous literature demonstrates the safety of primary repair in penetrating colon injury requiring resection, without the creation of a diverting ostomy. It is unknown whether a similar approach can be applied to patients with blunt colon injury. The aim of this study was to measure outcomes in patients who underwent colon resection with and without ostomy creation after blunt trauma injury to help direct future management. Using the National Trauma Data Bank for years 2008 to 2012, we identified patients with blunt trauma mechanisms who underwent colectomy. Patients were stratified into two groups: primary anastomosis and diversion with ostomy. Primary outcome was inpatient mortality. Secondary outcomes included length of stay and perioperative complications. All risk-adjusted analyses were performed using logistic regression with consideration of interactions. Five hundred eighty-one observations met our inclusion criteria. Baseline characteristics between the two groups were similar with the exception of age (37.3 vs 42.2 years, P < 0.001) and admission Glasgow coma score (13.2 vs 12.1, P = 0.002). Risk-adjusted mortality for the two groups was not statistically significant (2.3% vs 3.0%, P = 0.63); however, patients with primary anastomosis had a shorter length of stay (18.2 vs 28.1, P < 0.001), fewer days in the intensive care unit (10.9 vs 16.2, P < 0.001), and fewer ventilator days (10.5 vs 14.6, P = 0.01). In patients requiring colon resection after blunt trauma, mortality is not different for those who receive a primary anastomosis versus ostomy. Patients without diversion had shorter hospital stays, intensive care unit days, and ventilator days. These data support that primary anastomosis is safe in this patient population.
既往文献表明,对于需要切除的穿透性结肠损伤,一期修复是安全的,无需行转流造口术。对于钝性结肠损伤患者,能否采用类似方法尚不清楚。本研究的目的是评估钝性创伤后行结肠切除且有或无造口术患者的预后,以指导未来的治疗。利用2008年至2012年的国家创伤数据库,我们确定了因钝性创伤机制而行结肠切除术的患者。患者被分为两组:一期吻合组和造口转流组。主要结局是住院死亡率。次要结局包括住院时间和围手术期并发症。所有风险调整分析均采用逻辑回归,并考虑交互作用。581例观察对象符合我们的纳入标准。两组间的基线特征相似,但年龄(37.3岁对42.2岁,P<0.001)和入院时格拉斯哥昏迷评分(13.2对12.1,P=0.002)除外。两组的风险调整死亡率无统计学差异(2.3%对3.0%,P=0.63);然而,一期吻合的患者住院时间较短(18.2天对28.1天,P<0.001),重症监护病房天数较少(10.9天对16.2天,P<0.001),呼吸机使用天数较少(10.5天对14.6天,P=0.01)。在钝性创伤后需要结肠切除的患者中,接受一期吻合与造口术的患者死亡率无差异。未行转流的患者住院时间、重症监护病房天数和呼吸机使用天数较短。这些数据支持一期吻合在该患者群体中是安全的。