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需要切除的钝性创伤性结肠损伤的当代趋势和结果。

Contemporary Trends and Outcomes of Blunt Traumatic Colon Injuries Requiring Resection.

机构信息

Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, Los Angeles, California.

Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, Los Angeles, California.

出版信息

J Surg Res. 2020 Mar;247:251-257. doi: 10.1016/j.jss.2019.10.017. Epub 2019 Nov 25.

Abstract

BACKGROUND

After traumatic injury, primary anastomosis after colon resection has overtaken ostomy diversion. Improved technology facilitating primary anastomosis speed and integrity may have driven this change. Trends in ostomy versus anastomosis have yet to be quantified, and recent literature comparing outcomes is incomplete.

METHODS

The National Trauma Databank (2007-2014) was queried for all blunt colon injuries requiring resection. Patients were dichotomized into study groups based on whether they underwent ostomy creation. Ostomy creation frequency was compared over time. After subgrouping patients by colon injury location, multivariate regression adjusted for baseline characteristics and evaluated the impact of ostomy on clinical outcomes.

RESULTS

A total of 13,949 colon injuries requiring colectomy were identified. Ostomy frequency did not vary by study year (P = 0.536). Univariate analysis showed that patients undergoing ostomy were older (median, 40 versus 32; P < 0.001) and more often had comorbidities (65% versus 56%; P < 0.001). Multivariate analysis showed that ostomy creation was significantly associated with lower mortality after sigmoid colon injury (odds ratio, 0.512; P = 0.011) and higher rates of unplanned reoperation after transverse colon injury (odds ratio, 3.135; P = 0.048). Across all colon injuries, ostomies were significantly associated with longer hospital length of stay, intensive care unit length of stay, and ventilator days.

CONCLUSIONS

Ostomy creation for colonic injury has reached an equilibrium trough. The impact of ostomy creation varies by not only clinical outcome but also injury location. Further study is needed to define the optimal surgical management for blunt colon injuries requiring resection.

摘要

背景

在创伤后,结肠切除术后的一期吻合术已经超过了肠造口术。促进一期吻合术速度和完整性的技术改进可能推动了这一变化。肠造口术与吻合术的趋势尚未量化,最近比较结果的文献也不完整。

方法

从国家创伤数据库(2007-2014 年)中查询所有需要结肠切除的钝性结肠损伤患者。根据是否进行造口术将患者分为研究组。比较随时间推移的造口术发生频率。根据结肠损伤部位对患者进行亚组分析后,多变量回归调整基线特征,并评估造口术对临床结局的影响。

结果

共确定 13949 例需要结肠切除术的结肠损伤。造口术的频率在研究年内没有变化(P=0.536)。单因素分析显示,接受造口术的患者年龄较大(中位数,40 岁比 32 岁;P<0.001),合并症更多(65%比 56%;P<0.001)。多变量分析显示,在乙状结肠损伤后,造口术的创建与死亡率显著降低相关(优势比,0.512;P=0.011),在横结肠损伤后,计划性再手术的发生率显著升高(优势比,3.135;P=0.048)。在所有结肠损伤中,造口术与住院时间、重症监护病房时间和呼吸机使用时间的延长显著相关。

结论

结肠损伤的造口术已达到平衡谷。造口术的影响不仅取决于临床结局,还取决于损伤部位。需要进一步研究以确定需要切除的钝性结肠损伤的最佳手术治疗方法。

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