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无阻塞性冠状动脉疾病的糖尿病酮症酸中毒患者肌钙蛋白I水平升高

Elevated Troponin I Levels in Diabetic Ketoacidosis Without Obstructive Coronary Artery Disease.

作者信息

Manikkan Ajaydas T

机构信息

John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois.

出版信息

J Endocr Soc. 2018 Jul 19;2(9):1020-1023. doi: 10.1210/js.2018-00152. eCollection 2018 Sep 1.

Abstract

Elevated troponin levels have been observed in a wide spectrum of patients who do not have ischemic heart disease, including nonacute coronary syndrome and cardiovascular and noncardiovascular conditions. The cases of two patients with diabetic ketoacidosis who had elevated troponin levels in the absence of coronary artery disease are presented. This clinical scenario can pose a diagnostic dilemma for the physician. The objective of the present report is to highlight the mechanism of troponin elevation in patients with diabetic ketoacidosis, in addition to the clinical and prognostic significance of this finding.

摘要

在众多没有缺血性心脏病的患者中都观察到肌钙蛋白水平升高,这些患者包括非急性冠状动脉综合征以及心血管和非心血管疾病患者。本文介绍了两名糖尿病酮症酸中毒患者在无冠状动脉疾病情况下肌钙蛋白水平升高的病例。这种临床情况可能给医生带来诊断难题。本报告的目的是除了强调这一发现的临床和预后意义外,还突出糖尿病酮症酸中毒患者肌钙蛋白升高的机制。

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