Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Brazil.
Departamento de Ciências da Vida, Universidade do Estado da Bahia, Salvador, Brazil.
Parasite Immunol. 2019 Jun;41(6):e12588. doi: 10.1111/pim.12588. Epub 2018 Oct 8.
Brazil is a middle-income country undergoing the epidemiological transition. Effects of changes in daily life habits and access to clean water, sanitation and urban services on a growing urban population have contributed to a double burden of both infectious and noncommunicable chronic diseases. Studies have indicated that parasite infections may modulate the human immune system and influence the development of allergic conditions such as asthma. However, there is no consensus in the published literature on the effects of parasitic infections on allergy, perhaps as a consequence of factors determining the epidemiology of these infections that vary between populations such as age of first infection, duration and chronicity of infections, parasite burden and species, and host genetic susceptibility. In this review, we discuss the observations from Brazil concerning the relationship between parasite infections and allergy.
巴西是一个中等收入国家，正在经历着流行病学转变。日常生活习惯的改变以及清洁水、卫生和城市服务的普及，对不断增长的城市人口产生了影响，导致传染病和非传染性慢性疾病的双重负担。研究表明，寄生虫感染可能会调节人体免疫系统，并影响哮喘等过敏性疾病的发展。然而，在已发表的文献中，对于寄生虫感染对过敏的影响尚无共识，这可能是由于决定这些感染流行病学的因素在不同人群中存在差异，例如初次感染的年龄、感染的持续时间和慢性程度、寄生虫负担和种类以及宿主遗传易感性等。在这篇综述中，我们讨论了巴西有关寄生虫感染与过敏之间关系的观察结果。
