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Dose Reduction May Jeopardize Efficacy of Abiraterone Acetate.

作者信息

Woei-A-Jin F J Sherida H, Van Nieuwenhuyse Tine, van Erp Nielka P, Beuselinck Benoit, Stroobants Stephanie, Moes Dirk Jan A R, Osanto Susanne, Spriet Isabel

机构信息

F.J. Sherida H. Woei-A-Jin, University Hospitals Leuven, Leuven, Belgium; and Leiden University Medical Center, Leiden, the Netherlands; Tine Van Nieuwenhuyse, University Hospitals Leuven; and Katholieke Universiteit Leuven, Leuven, Belgium; Nielka P. van Erp, Radboud University Medical Center, Nijmegen, the Netherlands; Benoit Beuselinck and Stephanie Stroobants, University Hospitals Leuven, Leuven, Belgium; Dirk Jan A.R. Moes and Susanne Osanto, Leiden University Medical Center, Leiden, the Netherlands; and Isabel Spriet, University Hospitals Leuven; and Katholieke Universiteit Leuven, Leuven, Belgium.

出版信息

J Clin Oncol. 2018 Oct 20;36(30):3062-3064. doi: 10.1200/JCO.2018.79.3182. Epub 2018 Sep 6.

DOI:10.1200/JCO.2018.79.3182
PMID:30188790
Abstract
摘要

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Low-Dose Abiraterone Regimen: Drug Monitoring Might Be the Key.低剂量阿比特龙治疗方案:药物监测可能是关键。
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There Is Now Compelling Evidence to Further Evaluate Lower Doses of Abiraterone Acetate in Men With Metastatic Prostate Cancer: It Should Be Safer, May Be as Effective and Less Expensive.现有令人信服的证据表明,应进一步评估低剂量醋酸阿比特龙用于转移性前列腺癌男性患者的情况:它可能更安全,或许同样有效且成本更低。
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Low-Fat Abiraterone Food Effect Is of Great Consequence.低脂阿比特龙的食物效应至关重要。
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Low-Fat Abiraterone Food Effect Is of Little Consequence.低脂肪阿比特龙的食物效应影响不大。
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A multicenter retrospective analysis of sequential treatment of abiraterone acetate followed by docetaxel in Japanese patients with metastatic castration-resistant prostate cancer.一项关于日本转移性去势抵抗性前列腺癌患者中醋酸阿比特龙序贯多西他赛治疗的多中心回顾性分析。
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Prostate cancers that 'Wnt' respond to abiraterone.对阿比特龙有反应的前列腺癌“Wnt”。 (此译文感觉不太符合正常逻辑表达,可能原文表述有误,正常准确的可能是“对阿比特龙有反应的Wnt相关前列腺癌”之类的,但按要求严格翻译就是这样了)
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